Recombinant Mouse Interleukin 1 Receptor, Type II
Cat.No. : | Il1r2-1754M |
- Specification
- Gene Information
- Related Products
Cat. No. : | Il1r2-1754M |
Description : | Interleukin 1 receptor type II (IL1R2), also known as CD121b (Cluster of Differentiation 121b), is a transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. It is a decoy receptor known for its ability to buffer IL-1 effects. IL-1RII is involved in the control of the proinflammatory state that takes place in the endometrium during the premenstrual and menstrual periods. IL-1RII can neutralize IL-1 beta and counteract its effect on endometrial stromal cells, and may provide a new clinical strategy for the treatment of endometriosis. |
Molecular Weight : | The predicted molecular weight of Recombinant Mouse IL-1 RII is Mr 64.7 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa. |
Source : | Sf 21 Insect Cells. |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | Il1r2 interleukin 1 receptor, type II [ Mus musculus ] |
Synonyms : | Il1r2; interleukin 1 receptor, type II; CD121b; Il1r-2; IL-1 receptor beta chain |
Gene ID : | 16178 |
mRNA Refseq : | NM_010555 |
Protein Refseq : | NP_034685 |
UniProt ID : | P27931 |
Chromosome Location : | 1 B; 1 19.5 cM |
Pathway : | Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; MAPK signaling pathway |
Function : | interleukin-1 receptor activity; interleukin-1, Type II, blocking receptor activity; receptor activity |
Products Types
◆ Recombinant Protein | ||
IL1R2-306H | Recombinant Human IL1R2 Protein, His-tagged | +Inquiry |
Il1r2-8700M | Active Recombinant Mouse Il1r2 protein(Met1-Glu355), His-tagged | +Inquiry |
IL1R2-2688R | Recombinant Rat IL1R2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL1R2-166H | Recombinant Human IL1R2 Protein (ECD), His-tagged(C-ter) | +Inquiry |
IL1R2-165H | Recombinant Human IL1R2 Protein (ECD), Fc-His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL1R2-1376MCL | Recombinant Mouse IL1R2 cell lysate | +Inquiry |
IL1R2-1302RCL | Recombinant Rat IL1R2 cell lysate | +Inquiry |
IL1R2-834CCL | Recombinant Canine IL1R2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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