Recombinant Mouse LOXL2 Protein (26-776 aa), His-tagged
Cat.No. : | LOXL2-630M |
Product Overview : | Recombinant Mouse LOXL2 Protein (26-776 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length of Mature Protein. |
- Specification
- Gene Information
- Related Products
Description : | Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in Extracellular domain matrix, promotes cross-linking of Extracellular domain matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (T) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3 . Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.1 Publication. |
Source : | E. coli |
Species : | Mouse |
Tag : | His |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 88.4 kDa |
Protein length : | 26-776 aa |
AA Sequence : | QYEGWPYQLQYPEYFQQPAPEHHQR QVPSDVVKIQVRLAGQKRKHNEGRV EVYYEGQWGTVCDDDFSIHAAHVVC RQVGYVEAKSWAASSSYGPGEGPIW LDNIYCTGKESTLASCSSNGWGVTD CKHTEDVGVVCSEKRIPGFKFDNSL INQIESLNIQVEDIRIRPILSAFRH RKPVTEGYVEVKEGKAWKQICNKHW TAKNSHVVCGMFGFPAEKTYNPKAY KTFASRRKLRYWKFSMNCTGTEAHI SSCKLGPSVTRDPVKNATCENGQPA VVSCVPSQIFSPDGPSRFRKAYKPE QPLVRLRGGAQVGEGRVEVLKNGEW GTICDDKWDLVSASVVCRELGFGTA KEAITGSRLGQGIGPIHLNEVQCTG TEKSIIDCKFNTESQGCNHEEDAGV RCNIPIMGFQKKVRLNGGRNPYEGR VEVLTERNGSLVWGTVCGQNWGIVE AMVVCRQLGLGFASNAFQETWYWHG NIFANNVVMSGVKCSGTELSLAHCR HDEEVACPEGGVRFGAGVACSETAP DLVLNAEIVQQTAYLEDRPMSLLQC AMEENCLSASAVHTDPTRGHRRLLR FSSQIHNNGQSDFRPKNGRHAWIWH DCHRHYHSMEVFTYYDLLSLNGTKV AEGHKASFCLEDTECEGDIQKSYEC ANFGEQGITMGCWDMYRHDIDCQWI DITDVPPGDYLFQVVINPNYEVPES DFSNNIMKCRSRYDGYRIWMYNCHV GGAFSEETEQKFEHFSGLLNNQLSV Q |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | Loxl2 lysyl oxidase-like 2 [ Mus musculus ] |
Official Symbol : | LOXL2 |
Synonyms : | LOXL2; 1110004B06Rik; 4930526G11Rik; 9430067E15Rik; MGC102220; |
Gene ID : | 94352 |
mRNA Refseq : | NM_033325 |
Protein Refseq : | NP_201582 |
UniProt ID : | P58022 |
Products Types
◆ Recombinant Protein | ||
LOXL2-3375H | Recombinant Human LOXL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
LOXL2-797H | Recombinant Human LOXL2 Protein, Fc-tagged | +Inquiry |
LOXL2-1447M | Recombinant Mouse LOXL2 Protein (26-776 aa), His-tagged | +Inquiry |
LOXL2-37H | Recombinant Human LOXL2 Protein, N-8His tagged, Biotinylated | +Inquiry |
Loxl2-274M | Recombinant Mouse Loxl2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
LOXL2-1854HCL | Recombinant Human LOXL2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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