Recombinant Mouse MmP8 protein(Phe21-Ser465)

• Cat.No.: MmP8-1187M
• Product Overview: Recombinant Mouse MMP8 (NP_032637.3) (Phe 21-Ser 465) was expressed and purified in HEK293, with an initial Met at the N-terminus.

Specification

• Source: HEK293
• Species: Mouse
• Tag: N/A
• Protein length: Phe21-Ser465
• Form: Lyophilized from sterile 50 mM Tris, 50 mM NaCl, 10 mM CaCl2, 0.05 % Brij 35, pH 7. 5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant mouse MMP8 consisting of 446 amino acids and has a calculated molecular mass of 52 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 85 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Mmp8 matrix metallopeptidase 8 [ Mus musculus ]
• Official Symbol: MmP8
• Synonyms: MMP8; matrix metallopeptidase 8; neutrophil collagenase; MMP-8; collagenase 2; collagenase-2; matrix metalloproteinase 8; matrix metalloproteinase-8; BB138268
• Gene ID: 17394
• mRNA Refseq: NM_008611
• Protein Refseq: NP_032637

Reviews

04/03/2022

The use of MMP8 as a catalyst can significantly increase the rate and yield of chemical reactions with impressive high catalytic efficiency.

09/14/2021

MMP8 is really impressive, the results of every experiment are very consistent, you can see that its production process is very careful.

03/20/2021

MMP8 are inexpensive to prepare and cost-effective, making them ideal for our study.

Q&As

What signaling pathways does the MMP8 protein interact with?

The MMP8 protein interacts with a variety of signaling pathways, including TNF-α, TGF-β, Wnt, and NF-κB.

What drugs interact with the MMP8 protein?

A number of inhibitors and modulators of MMP8 protein have been developed for the regulation of MMP8 activity and the treatment of related diseases.

Why does MMP8 protein play a role in tissue repair?

The MMP8 protein is involved in the tissue repair and wound healing process, by degrading damaged tissue and supporting the formation of new tissue.

What is the mechanism of action of MMP8 protein in inflammatory response?

MMP8 protein is involved in regulating the production of inflammation-related molecules and cell infiltration, promoting the occurrence and maintenance of inflammatory response.

Does MMP8 have a role in post-traumatic recovery?

MMP8 protein is involved in the inflammatory and remodeling processes of post-traumatic wound healing, contributing to wound repair and tissue regeneration.

Does the MMP8 protein study have implications for new drug development?

MMP8 protein plays an important role in the occurrence and progression of diseases, and studying the regulatory mechanism of MMP8 protein is helpful for the development of new drugs, such as inhibitors targeting MMP8 protein may be applied to the treatment of related diseases