Recombinant Mouse Ppp2r5b Protein, Myc/DDK-tagged

• Cat.No.: Ppp2r5b-5079M
• Product Overview: Purified recombinant protein of mouse full-length protein phosphatase 2, regulatory subunit B', beta (Ppp2r5b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 57.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ppp2r5b protein phosphatase 2, regulatory subunit B', beta [ Mus musculus (house mouse) ]
• Official Symbol: Ppp2r5b
• Synonyms: PPP2R5B; protein phosphatase 2, regulatory subunit B (B56), beta isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; Bbeta; BC026670
• Gene ID: 225849
• mRNA Refseq: NM_198168
• Protein Refseq: NP_937811
• UniProt ID: Q6PD28