Recombinant Mouse Rnase1 Protein, His/GST-tagged

• Cat.No.: Rnase1-395M
• Product Overview: Recombinant Mouse Rnase1(Arg26~Val149) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Description: Rnase1 played an important role in many functions.
• Source: E. coli
• Species: Mouse
• Tag: His/GST
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 46.0kDa
• Identity: Reconstitute in PBS or others
• Protein length: Arg26~Val149
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: Rnase1 ribonuclease, RNase A family, 1 (pancreatic) [ Mus musculus ]
• Official Symbol: Rnase1
• Synonyms: RNASE1; ribonuclease, RNase A family, 1 (pancreatic); ribonuclease pancreatic; RNase 1; RNase A; ribonuclease 1, pancreatic; Rib1; Rib-1; AI574248
• Gene ID: 19752
• mRNA Refseq: NM_011271
• Protein Refseq: NP_035401

Reviews

10/27/2022

RNASE1 have strong anti-contamination ability and are not easily contaminated, which ensures the quality of the product.

07/06/2021

This stability of RNASE1 is impressive, maintaining stable performance regardless of the environment, demonstrating excellent quality and reliability.

01/08/2020

The catalytic activity of RNASE1 is excellent, which can simplify complex chemical reactions and improve yields, and has high scientific research value.

Q&As

Is there an association between RNASE1 protein and insulin secretion?

There is a correlation between RNASE1 protein and insulin secretion. Studies have shown that RNASE1 protein can regulate insulin synthesis and secretion by affecting the internal environment of pancreatic islets.

Is there a regulatory mechanism for RNASE1 proteins?

At present, the regulatory mechanism of RNASE1 protein is poorly understood. However, studies have found that some factors such as glucagon and insulin may be involved in regulating the expression and activity of RNASE1 protein.

Does RNASE1 protein have anti-tumor effects?

The RNASE1 protein is thought to have potential for anti-tumor effects. Studies have shown that it can induce apoptosis of tumor cells and inhibit the proliferation and invasion ability of tumor cells.

What are the applications of RNASE1 protein in clinical diagnosis?

RNASE1 protein has certain application potential in clinical diagnosis. Its hydrolyzed RNA properties can be used to measure the content and stability of RNA, and then evaluate the condition and treatment effect of certain diseases.

What role does RNASE1 protein play in RNA degradation?

The RNASE1 protein participates in the RNA degradation process in the digestive system by cutting the phosphodiester bond of the RNA molecule and degrading it into shorter RNA fragments.

Is RNASE1 protein also expressed in the gut?

The main expression and secretion site of RNASE1 protein is the pancreas, while the expression in the gut is relatively low. But in some cases, other nucleases in the gut may perform a similar function.