Recombinant Mouse TXNIP Protein (1-397 aa), His-tagged
Cat.No. : | TXNIP-1689M |
Product Overview : | Recombinant Mouse TXNIP Protein (1-397 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) . Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. |
Source : | Yeast |
Species : | Mouse |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 46.4 kDa |
Protein length : | 1-397 aa |
AA Sequence : | MVMFKKIKSFEVVFNDPEKVYGSGE KVAGRVIVEVCEVTRVKAVRILACG VAKVLWMQGSQQCKQTLDYLRYEDT LLLEEQPTAGENEMVIMRPGNKYEY KFGFELPQGPLGTSFKGKYGCVDYW VKAFLDRPSQPTQEAKKNFEVMDLV DVNTPDLMAPVSAKKEKKVSCMFIP DGRVSVSARIDRKGFCEGDDISIHA DFENTCSRIVVPKAAIVARHTYLAN GQTKVFTQKLSSVRGNHIISGTCAS WRGKSLRVQKIRPSILGCNILKVEY SLLIYVSVPGSKKVILDLPLVIGSR SGLSSRTSSMASRTSSEMSWIDLNI PDTPEAPPCYMDIIPEDHRLESPTT PLLDDVDDSQDSPIFMYAPEFQFMP PPTYTEVDPCVLNNNNNNNNVQ |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | Txnip thioredoxin interacting protein [ Mus musculus ] |
Official Symbol : | TXNIP |
Synonyms : | TXNIP; THIF; Tbp-2; VDUP1; Hyplip1; AA682105; 1200008J08Rik; |
Gene ID : | 56338 |
mRNA Refseq : | NM_001009935 |
Protein Refseq : | NP_001009935 |
UniProt ID : | Q8BG60 |
Products Types
◆ Recombinant Protein | ||
TXNIP-4853R | Recombinant Rhesus Macaque TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
Txnip-6750M | Recombinant Mouse Txnip Protein, Myc/DDK-tagged | +Inquiry |
TXNIP-9790M | Recombinant Mouse TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
TXNIP-6032R | Recombinant Rat TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
TXNIP-2283H | Recombinant Human TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TXNIP-620HCL | Recombinant Human TXNIP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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