Recombinant Mouse Txnip Protein, Myc/DDK-tagged
Cat.No. : | Txnip-6750M |
Product Overview : | Purified recombinant protein of mouse full-length thioredoxin interacting protein (Txnip), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 44.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Txnip thioredoxin interacting protein [ Mus musculus (house mouse) ] |
Official Symbol : | Txnip |
Synonyms : | TXNIP; thioredoxin interacting protein; thioredoxin-interacting protein; hyperlipidemia 1; thioredoxin binding protein-2; vitamin D3 up-regulated protein 1; upregulated by 1,25-dihydroxyvitamin D-3; THIF; Tbp-2; VDUP1; Hyplip1; AA682105; 1200008J08Rik |
Gene ID : | 56338 |
mRNA Refseq : | NM_023719 |
Protein Refseq : | NP_076208 |
UniProt ID : | Q8BG60 |
Products Types
◆ Recombinant Protein | ||
TXNIP-2283H | Recombinant Human TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
TXNIP-4853R | Recombinant Rhesus Macaque TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
TXNIP-9790M | Recombinant Mouse TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
TXNIP-1689M | Recombinant Mouse TXNIP Protein (1-397 aa), His-tagged | +Inquiry |
TXNIP-6032R | Recombinant Rat TXNIP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TXNIP-620HCL | Recombinant Human TXNIP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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