Recombinant Pig ANGPT2 Protein, N-His tagged

• Cat.No.: ANGPT2-01P
• Product Overview: Recombinant Pig ANGPT2 Protein with N-His tag was expressed in Mammalian cell.

Specification

• Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. Involved in the regulation of lymphangiogenesis.
• Source: Mammalian cell
• Species: Pig
• Tag: N-His
• Molecular Mass: 56 kDa
• AA Sequence: HHHHHHHHYNNFRKSMDSTGKRQYQ VQHGPCSYTFLLPETDNCRSPSSSY VSNAVQRDAPLDYDDSVRRLQVLEN IMENNTQWLMKLESYIQDNMKKEMV EIQQNAVQNQTAVMIEIGTNLLNQT AEQTRKLTDVEAQVLNQTTRLELQL LEHSLSTNKLEKQILDQTSEINKLQ DKNSFLEKKVLDMEDKHIVQLQSIK EEKDQLQVLVSKQNSIIEELEKQLV TATVNNSVLQKQQHDLMETVHNLLT MISTSNSAKHSLVAKEEQIIFRDCA EAFKSGLTTSGTYTLTFPNSTEETK AYCDMETGGGGWTVIQRREDGSVDF QRTWKEYKMGFGSPSGEHWLGNEFV SQVTNQKRYVLKIHLRDWEGNEAYS LYEHFYLSSEEFNYRIHLKGLTGTA GKISSISQPGNDFSTKDADNDKCIC KCSQMLTGGWWFDACGPSNLNGMYY PQRQNTNKFNGIKWYYWKGSGYSLK ATTMMIRPADF
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.19 mg/mL by BCA
• Storage Buffer: Sterile PBS, pH 7.4

Gene Information

• Gene Name: ANGPT2 angiopoietin 2 [ Sus scrofa (pig) ]
• Official Symbol: ANGPT2
• Synonyms: ANGPT2; angiopoietin 2; ANG2; angiopoietin-2; ANG-2
• Gene ID: 396730
• mRNA Refseq: NM_213808
• Protein Refseq: NP_998973
• UniProt ID: Q9BDY7