Recombinant Pig CAPN2 Protein, His-tagged
Cat.No. : | CAPN2-001P |
Product Overview : | Full length pig CAPN2 recombinant protein with His-SUMO-tag was expressed in E.coli. |
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Description : | The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. |
Source : | E. coli |
Species : | Pig |
Tag : | His |
AA Sequence : | YPNTFWMNPQYLIKLEEEDEDQEDG ESGCTFLVGLIQKHRRRQRKMGEDM HTIGFGIYEVPEELTGQTNIHLSKN FFLTHRARERSDTFINLREVLNRFK LPPGEYILVPSTFEPNKDGDFCIRV FSEKKADYQVVDDEIEADLEENDAS EDDIDDGFRRLFAQLAGEDAEISAF ELQTILRRVLAKRQDIKSDGFSIET CRIMVDMLDSDGSAKLGLKEFYILW TKIQKYQKIYREIDVDRSGTMNSYE MRKALEEAGFKLPCQLHQVIVARFA DDQLIIDFDNFVRCLVRLETLFRIS KQLDSENTGTIELDLISWLCFSVL |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Storage : | Store at -20 to -80 centigrade. |
Storage Buffer : | Tris-based buffer, 50% glycerol |
Gene Name : | CAPN2 calpain 2 [ Sus scrofa (pig) ] |
Official Symbol : | CAPN2 |
Synonyms : | CAPN2; calpain 2; calpain-2 catalytic subunit; CANP 2; M-calpain; calcium-activated neutral proteinase 2; calpain II; calpain M-type; calpain-2 large subunit; millimolar-calpain; EC 3.4.22.53 |
Gene ID : | 397393 |
mRNA Refseq : | NM_001100188 |
Protein Refseq : | NP_001093658 |
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◆ Native Protein | ||
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCAPN2 activity is tightly regulated by intracellular calcium levels and various other factors to maintain cellular homeostasis.
CAPN2 interacts with various cellular proteins, contributing to processes like protein degradation, cytoskeletal remodeling, and cell signaling, influencing disease pathways.
Research suggests that modulating CAPN2 activity could be a potential therapeutic strategy for managing diseases associated with its dysregulation.
Some compounds and inhibitors targeting CAPN2 have been developed in preclinical studies, showing promise in controlling its activity for therapeutic purposes.
In some cases, altered levels of CAPN2 have been observed in disease states, suggesting its potential as a biomarker, but further validation is needed.
Customer Reviews (3)
Write a reviewThe CAPN2 protein has been extensively studied and validated in various experimental applications.
Their team of technical experts possess deep knowledge and expertise regarding the protein, ensuring that researchers receive accurate and timely assistance.
In addition to its advantages in trials, the manufacturer of the CAPN2 protein offers exceptional support to researchers.
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