Recombinant Pig IL17A Protein (Gly26-Ser155), C-His tagged, Animal-free, Carrier-free

• Cat.No.: IL17A-15P
• Product Overview: Recombinant Pig IL17A Protein (Gly26-Ser155) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Interleukin 17-alpha (IL-17A) is a 14.54 kDa cytokine with 131 amino acid residues and is also referred to as CTLA-8. IL-17A is a proinflammatory cytokine mainly expressed in Th 17 cells, NK cells, and innate lymphoid cells (ILCs). After binding to the IL-17 receptor, IL-17A stimulates the production of IL-6, cyclooxygenase-2 (COX-2), and nitric oxide (NO) by activating NF-κB and MAPK signaling pathways. In addition, it also plays an essential role in against infection of extracellular bacteria and fungi by inducing epithelial cells to produce antimicrobial peptides.
• Source: E. coli
• Species: Pig
• Tag: C-His
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 15.81 kDa.
  The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: Gly26-Ser155
• Endotoxin: < 0.01 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: IL17A interleukin 17A [ Phacochoerus africanus (Common warthog) ]
• Official Symbol: IL17A
• Synonyms: IL17A; interleukin 17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8; Il17; Ctla8; IL-17; Ctla-8; IL-17A
• Gene ID: 125136096
• mRNA Refseq: XM_047796735
• Protein Refseq: XP_047652691