Recombinant Rat ACAA1B Protein

• Cat.No.: ACAA1B-433R
• Product Overview: Recombinant Rat ACAA1B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Rat
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Acaa1b acetyl-Coenzyme A acyltransferase 1B [ Rattus norvegicus ]
• Official Symbol: ACAA1B
• Gene ID: 501072
• mRNA Refseq: NM_001040019.1
• Protein Refseq: NP_001035108.1
• UniProt ID: P07871

Reviews

03/30/2022

Shows good stability and compatibility with various sample types and buffers.

09/05/2021

Demonstrates excellent specificity and sensitivity in detecting the target protein in sandwich ELISAs.

05/02/2016

Highly efficient in neutralizing the activity of the target protein in bioassays.

Q&As

What is the structure of the acetyl-Coenzyme A acyltransferase 1B protein?

The acetyl-Coenzyme A acyltransferase 1B protein structure is composed of an N-terminal domain, a central domain, and a C-terminal domain.

What is the tissue distribution of acetyl-Coenzyme A acyltransferase 1B expression?

Acetyl-Coenzyme A acyltransferase 1B is mainly expressed in liver and adipose tissue, but also in other tissues such as muscle and brain.

How is acetyl-Coenzyme A acyltransferase 1B involved in insulin sensitivity and diabetes?

Acetyl-Coenzyme A acyltransferase 1B is involved in regulating insulin sensitivity and glucose homeostasis, and dysregulation of this protein has been implicated in the development of diabetes.

How is acetyl-Coenzyme A acyltransferase 1B regulated?

Acetyl-Coenzyme A acyltransferase 1B is regulated by post-translational modifications, transcriptional regulation, and by various signaling pathways.

What is the role of acetyl-Coenzyme A acyltransferase 1B in lipid metabolism?

Acetyl-Coenzyme A acyltransferase 1B plays a key role in lipid metabolism by catalyzing the conversion of acetyl-CoA and fatty acid CoA thioesters to produce long-chain acyl-CoAs, which are then used for energy production or storage.

What are the substrates of acetyl-Coenzyme A acyltransferase 1B?

The substrates of acetyl-Coenzyme A acyltransferase 1B are acetyl-CoA and fatty acid CoA thioesters.

What diseases are associated with mutations in the acetyl-Coenzyme A acyltransferase 1B gene?

Mutations in the acetyl-Coenzyme A acyltransferase 1B gene have been associated with metabolic disorders such as obesity and insulin resistance.

What is the relationship between acetyl-Coenzyme A acyltransferase 1B and fatty acid synthesis?

Acetyl-Coenzyme A acyltransferase 1B is not directly involved in fatty acid synthesis, but it plays a role in the regulation of fatty acid metabolism and the synthesis of complex lipids.

What is the function of acetyl-Coenzyme A acyltransferase 1B protein?

The function of acetyl-Coenzyme A acyltransferase 1B protein is to catalyze the conversion of acetyl-CoA and fatty acid CoA thioesters to produce long-chain acyl-CoAs.

What is the evolutionary history of the acetyl-Coenzyme A acyltransferase 1B gene and protein?

The acetyl-Coenzyme A acyltransferase 1B gene and protein are conserved throughout evolution and are found in a wide range of organisms, from bacteria to humans.