Recombinant Rat AP4M1 Protein Pre-coupled Magnetic Beads

• Cat.No.: AP4M1-360R-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Rat
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Ap4m1 adaptor-related protein complex 4, mu 1 subunit [ Rattus norvegicus ]
• Official Symbol: AP4M1
• Gene ID: 304344
• mRNA Refseq: NM_001037977.1
• Protein Refseq: NP_001033066.1
• UniProt ID: Q2PWT8

Reviews

04/12/2022

The short half-life and high clearance characteristics of AP4M1 enable it to better control the concentration and duration of action of the drug in the body, so as to better grasp the therapeutic effect.

11/20/2021

High band strength of this protein in Western blot improves the signal-to-noise ratio of the experiment.

04/11/2021

After a long period of storage or repeated use, the stability of AP4M1 is still very good, indicating its high reliability and trustworthiness.

Q&As

How can AP4M1 protein be delivered to specific tissues or organs in the body?

Delivery systems, such as targeted nanoparticles or viral vectors, can potentially be used to specifically deliver AP4M1 protein to desired tissues or organs.

What is the current understanding of the structure of AP4M1 protein?

The structure of AP4M1 protein has been studied using techniques like X-ray crystallography, revealing important insights into its function.

How can the effects of AP4M1 protein be studied in animal models?

Animal models, such as mice with genetic modifications or knockouts, can help researchers investigate the role and impact of AP4M1 protein in various disease contexts.

Can AP4M1 be used for therapeutic purposes?

It is possible that AP4M1 could be used as a therapeutic agent in the future, but more research is needed.

How can AP4M1 protein expression be regulated within cells?

Various cellular mechanisms, such as transcription factors and signaling pathways, may regulate AP4M1 protein expression.

Are there any ongoing clinical trials involving AP4M1 protein?

At the moment, there are no known ongoing clinical trials involving AP4M1 protein, but it is an area of active research.

Can AP4M1 protein be used in combination with other therapeutic agents?

The possibility of combining AP4M1 protein with other therapeutic agents for synergistic effects could be explored in future studies.

Can AP4M1 protein be used for diagnostic purposes?

Detecting AP4M1 protein levels or mutations could potentially be used as a diagnostic tool for certain diseases or genetic disorders.

What are the potential applications of AP4M1 in cancer research?

AP4M1 protein may play a role in cancer cell migration and invasion, making it a potential target for cancer therapeutics or biomarkers.

What are the major challenges in producing AP4M1 at large scale?

Challenges may include optimizing protein purification methods, ensuring proper folding and functionality, and maintaining stability during production.

How can AP4M1 protein be effectively delivered to the brain for neurological disorders?

Strategies like using blood-brain barrier-penetrating nanoparticles or viral vectors could potentially enable the delivery of AP4M1 protein to the brain for neurological disorders.

What are the potential future directions for AP4M1 research?

Future research may focus on elucidating the molecular mechanisms of AP4M1, exploring its role in different diseases, and developing therapeutic strategies.

How is AP4M1 related to clinical conditions or diseases?

Mutations in the AP4M1 gene have been associated with a rare genetic disorder called AP-4 deficiency syndrome.

Are there any known natural compounds that can modulate AP4M1 protein activity?

Currently, there are no known natural compounds that have been identified as direct modulators of AP4M1 protein activity.

What is the function of AP4M1 protein in the human body?

AP4M1 is a subunit of the AP-4 complex, which plays a role in protein trafficking within cells.

How can AP4M1 protein be effectively targeted for drug development?

Understanding the three-dimensional structure of AP4M1 could provide valuable information for designing drugs that specifically target this protein.

How can the effects of AP4M1 protein be studied at the cellular level?

Techniques like CRISPR-Cas9 gene editing or siRNA knockdown can be employed to study the cellular effects of AP4M1 protein.

What are the potential side effects or risks associated with AP4M1 protein therapy?

As AP4M1 protein therapy is still in the early stages of research, potential side effects and risks are not yet fully understood and need further investigation.

Are there any known interactions between AP4M1 protein and other cellular proteins?

Yes, AP4M1 has been found to interact with other proteins within the AP-4 complex and in other cellular processes.

Are there any known inhibitors or activators of AP4M1 protein?

Currently, there are no known specific inhibitors or activators of AP4M1 protein, but research is ongoing in this area.