Recombinant Rat ARL8B Protein
Cat.No. : | ARL8B-788R |
Product Overview : | Recombinant Rat ARL8B full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Rat |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | Arl8b ADP-ribosylation factor-like 8B [ Rattus norvegicus ] |
Official Symbol : | ARL8B |
Gene ID : | 500282 |
mRNA Refseq : | NM_001024332.1 |
Protein Refseq : | NP_001019503.1 |
MIM : | |
UniProt ID : | Q66HA6 |
Products Types
◆ Recombinant Protein | ||
ARL8B-731M | Recombinant Mouse ARL8B Protein, His (Fc)-Avi-tagged | +Inquiry |
Arl8b-1712M | Recombinant Mouse Arl8b Protein, Myc/DDK-tagged | +Inquiry |
ARL8B-444R | Recombinant Rat ARL8B Protein, His (Fc)-Avi-tagged | +Inquiry |
ARL8B-301538H | Recombinant Human ARL8B protein, GST-tagged | +Inquiry |
ARL8B-1943M | Recombinant Mouse ARL8B Protein | +Inquiry |
◆ Lysates | ||
ARL8B-8704HCL | Recombinant Human ARL8B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (16)
Ask a questionThere are indications that ARL8B can influence cellular metabolism. It has been shown to regulate autophagy, a process involved in cellular recycling and metabolism. Modulation of ARL8B activity may impact metabolic processes, although further research is needed to fully understand its role in cellular metabolism.
ARL8B interacts with various proteins to carry out its functions. For example, it interacts with SKIP (SifA and kinesin-interacting protein) to regulate lysosomal trafficking and fusion with endocytic compartments.
Yes, ARL8B has been implicated in immune response pathways. It influences the trafficking and maturation of immune-related vesicles, such as phagolysosomes, which are involved in the processing of microbial pathogens.
While the specific role of ARL8B in neuronal development or function has not been extensively studied, its involvement in lysosomal trafficking and autophagy suggests it may have implications for neuronal homeostasis and pathology. Further research is needed to explore this connection.
Yes, ARL8B can undergo various post-translational modifications, such as phosphorylation and ubiquitination, which can regulate its activity and interactions with other cellular components.
Dysregulation of ARL8B expression or function has been implicated in certain diseases. For example, altered ARL8B expression has been observed in cancer cells and neurodegenerative disorders, suggesting its potential involvement in disease progression.
Yes, ARL8B is involved in maintaining cellular homeostasis by regulating processes such as lysosomal function, vesicle trafficking, autophagy, and endocytic recycling. Disruption of ARL8B function can lead to imbalances in these processes, potentially affecting cellular homeostasis.
Limited information is available on mutations or polymorphisms in the ARL8B gene. However, like other genes, variations such as single nucleotide polymorphisms (SNPs) may exist in the population, and their functional significance requires further investigation.
Yes, there are ARL8B knockout mouse models that have been generated to study its functions in vivo. These models provide valuable insights into the physiological roles of ARL8B and its implications in disease.
ARL8B is expressed in various tissues and cell types. Its expression levels may vary among different tissues, indicating potential tissue-specific regulation or functions.
Yes, ARL8B is involved in autophagy, promoting the fusion of autophagosomes with lysosomes for cargo degradation. It is essential for autophagosome-lysosome fusion and proper autophagic flux.
Yes, ARL8B plays a crucial role in intracellular vesicle transport. It facilitates the movement of vesicles along microtubules and regulates their fusion with target membranes, ensuring proper cargo delivery and organelle homeostasis.
Currently, there are no specific drugs or therapeutic interventions targeting ARL8B. However, as our understanding of its role in cellular processes and diseases advances, it may become a potential target for future drug development.
ARL8B's involvement in lysosomal trafficking and autophagy pathways suggests it may have potential as a target for drug delivery or nanomedicine approaches. Modulating ARL8B function could potentially enhance cargo delivery to specific cellular compartments. However, further research is needed to explore this possibility.
Targeting ARL8B for therapeutic purposes is an area of ongoing research. Given its involvement in cellular processes relevant to diseases, modulating ARL8B activity or interactions may hold potential for future therapeutic interventions.
There is emerging evidence linking ARL8B to neurodegenerative diseases such as Parkinson's disease. Altered ARL8B expression or function may disrupt lysosomal trafficking and autophagy, leading to accumulation of protein aggregates and neurotoxicity.
Customer Reviews (8)
Write a reviewThe manufacturer also ensures that the ARL8B protein is well-characterized, with extensive documentation on its functional properties.
the ease of use and compatibility of the ARL8B protein with various techniques further enhances its appeal.
It has become an indispensable tool in my experiments, consistently meeting my needs and providing valuable insights.
With its well-characterized nature and availability in various formats, the arnC protein is an advantageous tool that aids researchers in achieving their scientific goals.
the ARL8B protein is available in different formats, including recombinant and purified variants.
This flexibility allows researchers to select the most suitable form for their particular experimental setup, enhancing the efficiency and accuracy of their trials.
the ARL8B protein stands out for its excellent quality, exceptional technical support, and wide range of applications.
The ARL8B protein is a top-quality product that is sure to fulfill my experimental requirements.
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