Recombinant Rat Il2 protein(Ala21-Gln155)
Cat.No. : | Il2-747R |
Product Overview : | Recombinant Rat IL2 (P17108) (Ala 21-Gln 155) was expressed and purified in E. coli, with an initial Met at the N-terminus. |
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Source : | E. coli |
Species : | Rat |
Tag : | N/A |
Protein length : | Ala21-Gln155 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Measured by its ability to bind recombinant human IL2Ra-Fc in a functional ELISA. 2. Measured in a cell proliferation assay using CTLL2. The ED50 for this effect is typically 0.5-3 ng/mL. |
Molecular Mass : | The recombinant rat IL2 consisting of 136 amino acids and has a calculated molecular mass of 15.6 kDa. It migrates as an approximately 15 kDa band in SDS-PAGE under reducing conditions. |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Il2 interleukin 2 [ Rattus norvegicus ] |
Official Symbol : | Il2 |
Synonyms : | IL2; interleukin 2; interleukin-2; IL-2; TCGF; T-cell growth factor; |
Gene ID : | 116562 |
mRNA Refseq : | NM_053836 |
Protein Refseq : | NP_446288 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionIL2 promotes the formation of memory T-cells.
IL2 has a pro-tumorigenic role in the tumor microenvironment.
IL2 synergizes with IL-12 in a mixed cytokine environment.
IL2 upregulates the expression of PD-1 checkpoint inhibitors.
IL2 is rapidly internalized by activated T-cells.
IL2 induces M1 macrophage polarization.
IL2 increases blood-brain barrier permeability.
IL2's affinity for its receptor decreases under hypoxic conditions.
IL2's bioactivity is enhanced by glycosylation.
IL2 promotes the differentiation of Th17 cells.
Customer Reviews (3)
Write a reviewPotent in T-cell activation.
Suitable for cytokine assays.
High stability.
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