Recombinant Rat Il2 Protein, His-tagged

• Cat.No.: Il2-480R
• Product Overview: Recombinant Rat Il2 Protein(NP_446288.1)(Ala21-Gln155), fused to 6His tag at the C-terminus, was expressed in Mammalian expression system.

Specification

• Description: Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.
• Source: HEK293
• Species: Rat
• Tag: His
• Form: Supplied as a 0.2 μm filtered solution of 5mM NaH2PO4, 5mM Citric acid, 150mM NaCl, pH4.0.
• Molecular Mass: 14-16kDa, reducing conditions
• Protein length: Ala21-Gln155
• Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Store at ≤-70°C, stable for 6 months after receipt.
  Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
  Please minimize freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Shipping: The product is shipped on dry ice/polar packs.
  Upon receipt, store it immediately at the temperature listed below.

Gene Information

• Gene Name: Il2 interleukin 2 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Il2
• Synonyms: Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin; IL2
• Gene ID: 116562
• mRNA Refseq: NM_053836.1
• Protein Refseq: NP_446288.1
• UniProt ID: P17108