Recombinant Rat Pla2g2a protein, His & GST-tagged

• Cat.No.: Pla2g2a-8259R
• Product Overview: Recombinant Rat Pla2g2a aa. (Ser22~Cys146 (Accession # P14423)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: Hydrolyzes acyl group at the sn-2 position of phospholipids, forming non-esterified fatty acids and lysophospholipids; plays a critical role in inflammation; induces proliferation of smooth muscle cells.
• Source: E. coli
• Species: Rat
• Tag: His & GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 46.5kDa.
• Protein length: Ser22~Cys146 (Accession # P14423)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.6.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: Pla2g2a phospholipase A2 group IIA [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Pla2g2a
• Gene ID: 29692
• mRNA Refseq: NM_031598.3
• Protein Refseq: NP_113786.3
• UniProt ID: P14423

Reviews

11/23/2022

PLA2G2A's ability to easily attach to the surface of a cell or material.

06/14/2022

It has the characteristics of high safety in clinical treatment.

04/30/2022

The operation is very simple, get started quickly, easy to use, will recommend to others.

Q&As

How to use the expression pattern of PLA2G2A protein for disease diagnosis?

By detecting the expression pattern of PLA2G2A proteins, it can assist in the diagnosis of certain diseases, such as inflammatory diseases, cardiovascular diseases, cancer, etc.

What is the role of PLA2G2A proteins in the immune system?

PLA2G2A proteins have the role of regulating inflammatory response and apoptosis in the immune system, which can affect the survival and function of immune cells.

How to study the regulatory mechanisms of PLA2G2A proteins?

Studying the regulatory mechanism of PLA2G2A proteins requires a comprehensive use of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.

Is the expression of PLA2G2A protein related to the stage of disease development?

The expression of PLA2G2A protein may be related to the stage of the disease, and the expression level of the PLA2G2A protein may change at different stages of the disease development.

What are the types of mutations in PLA2G2A proteins?

The types of mutations in PLA2G2A proteins include point mutations, insertions/deletions, duplications, etc., which can lead to structural and functional abnormalities of the protein.

What is the relationship of PLA2G2A protein to other genes or proteins?

PLA2G2A proteins have complex relationships with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.