Recombinant Rhesus Macaque AK2 Protein Pre-coupled Magnetic Beads

• Cat.No.: AK2-111R-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Rhesus Macaque
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: AK2 adenylate kinase 2 [ Macaca mulatta (Rhesus monkey) ]
• Official Symbol: AK2
• Synonyms: AK2; adenylate kinase 2, mitochondrial
• Gene ID: 709737
• mRNA Refseq: NM_001261078
• Protein Refseq: NP_001248007
• UniProt ID: F7H131

Reviews

04/06/2023

The remarkable traits of the AK2 protein, combined with the manufacturer's top-tier assistance, allows me to delve deeper into my research objectives

03/08/2023

With the AK2 protein in my arsenal and the unwavering support of the manufacturer's technical team, I am empowered to overcome any hurdles that may obstruct my progress.

12/13/2022

With an unrivaled depth of knowledge and expertise, ensuring a seamless and successful research experience.

Q&As

Are there any drugs that target AK2 protein?

Currently, there are no FDA-approved drugs targeting AK2 specifically. However, ongoing research is exploring the development of AK2 inhibitors as potential anti-cancer therapies.

Are there any natural compounds or dietary factors that impact AK2 protein activity?

Some studies suggest that certain natural compounds and dietary factors, such as resveratrol, quercetin, and curcumin, can modulate AK2 protein activity. These compounds are known to exhibit antioxidant and anti-inflammatory properties, and their effects on AK2 activity may contribute to their potential health benefits.

How is AK2 protein regulated in the body?

AK2 protein activity can be regulated at multiple levels. It can be modulated by post-translational modifications, such as phosphorylation and acetylation, which can affect its enzymatic activity and protein stability. The expression of AK2 can also be regulated by various factors, including hormones, growth factors, and environmental stimuli.

How is AK2 protein studied in the lab?

AK2 protein is commonly studied using techniques such as gene cloning, recombinant protein expression, and enzymatic assays. Researchers also use cell and animal models to investigate the physiological and pathological roles of AK2 in various biological processes.

Is AK2 protein expressed in cancer cells?

AK2 protein expression levels can vary in different cancer types. Some studies have reported elevated AK2 expression in certain cancers, including leukemia, breast cancer, and colorectal cancer. However, more research is needed to fully understand the role of AK2 in cancer development and progression.

How does AK2 protein interact with other proteins in the cellular network?

AK2 can interact with various proteins in the cellular network, forming protein complexes involved in energy metabolism and other cellular processes. For example, it can interact with other enzymes involved in ATP production and utilization, as well as proteins involved in mitochondrial function and signaling pathways.

What are the other functions of AK2 protein besides energy metabolism?

Besides its role in energy metabolism, AK2 protein has been implicated in other cellular processes, such as DNA replication and repair, apoptosis (programmed cell death), and signal transduction. It may also play a role in maintaining cellular redox balance and regulating cellular differentiation.

How is AK2 protein related to diseases?

Mutations in the AK2 gene have been associated with several diseases, including reticular dysgenesis, a rare immunodeficiency disorder. In these cases, the dysfunctional AK2 enzyme impairs the production of ATP, leading to impaired immune system development and function.

What are the potential future research directions for AK2 protein?

Further research on AK2 protein may focus on understanding its role in cellular energy metabolism, exploring its involvement in other diseases, and developing targeted therapies to modulate its activity for therapeutic purposes.

Are there any therapies targeting AK2 protein currently in clinical trials?

As of now, there are no clinical trials specifically targeting AK2 protein. However, preclinical studies continue to explore the potential of AK2 inhibitors as therapeutic agents, particularly in cancer treatment. These inhibitors aim to disrupt the altered energy metabolism of cancer cells, which may provide a basis for future clinical trials.

Can AK2 protein be targeted for therapeutic purposes?

AK2 protein has gained attention as a potential therapeutic target for certain diseases. Inhibiting AK2 activity may be beneficial in specific cancer types, as cancer cells often rely on altered energy metabolism for their growth and survival.

Can AK2 protein be used as a diagnostic marker for diseases?

AK2 protein itself is not commonly used as a diagnostic marker for diseases. However, mutations in the AK2 gene have been linked to certain genetic disorders, such as reticular dysgenesis, and genetic testing for these mutations can be used for diagnostic purposes.

Where is AK2 protein found in the body?

AK2 protein is found in various tissues and organs throughout the body, including the heart, brain, liver, and skeletal muscles.