Recombinant Rhesus monkey CACUL1 Protein, His-tagged
Cat.No. : | CACUL1-605R |
Product Overview : | Recombinant Rhesus monkey CACUL1 full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Rhesus monkey |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC. |
Storage Buffer : | PBS buffer |
Gene Name : | CACUL1 CDK2-associated, cullin domain 1 [ Macaca mulatta (Rhesus monkey) ] |
Official Symbol : | CACUL1 |
Synonyms : | CACUL1; C10orf46; C9H10orf46; CDK2-associated and cullin domain-containing protein 1; |
Gene ID : | 702200 |
mRNA Refseq : | NM_001266943 |
Protein Refseq : | NP_001253872 |
MIM : | |
UniProt ID : | F7GNK2 |
Products Types
◆ Recombinant Protein | ||
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CACUL1-433R | Recombinant Rhesus Macaque CACUL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CACUL1-1078R | Recombinant Rat CACUL1 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCACUL1's subcellular localization varies throughout the cell cycle. It shuttles between the nucleus and cytoplasm, and this dynamic localization is essential for its role in cell cycle regulation and DNA damage response.
CACUL1 promotes cell cycle progression by forming complexes with CDKs and Cyclins, facilitating their activation. This leads to the phosphorylation of target proteins that drive the cell cycle forward.
CACUL1 interacts with several key cell cycle regulators, including Cyclin-Dependent Kinases (CDKs) and Cyclins. It also interacts with proteins involved in DNA damage repair and checkpoint control.
Emerging research suggests that CACUL1 is involved in epigenetic regulation by influencing chromatin remodeling processes. It can interact with histone modifiers and transcription factors, leading to changes in gene expression profiles in cancer cells. Understanding these epigenetic mechanisms is vital for targeted cancer therapies.
CACUL1 expression is tightly regulated at the transcriptional level. It is upregulated in many cancer types due to aberrant transcriptional activation, which can be driven by various oncogenic pathways.
Customer Reviews (3)
Write a reviewProduct exceeded my expectations!
Easy to use and effective.
Great value for the price.
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