Recombinant Zebrafish ACOT9.1

• Cat.No.: ACOT9.1-2886Z
• Product Overview: Recombinant Zebrafish ACOT9.1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: acot9.1 acyl-CoA thioesterase 9, tandem duplicate 1 [ Danio rerio (zebrafish) ]
• Official Symbol: ACOT9.1
• Gene ID: 798073
• mRNA Refseq: NM_001020744
• Protein Refseq: NP_001018580
• UniProt ID: Q503Q9

Q&As

Can ACOT9.1 protein be used for the treatment of mitochondrial disorders?

There is currently no evidence to suggest that ACOT9.1 protein can be used for the treatment of mitochondrial disorders. However, further research is needed to investigate the potential role of ACOT9.1 in mitochondrial function and to determine whether it could be a suitable target for the development of therapies for mitochondrial disorders.

Can ACOT9.1 protein be used for the treatment of metabolic disorders?

ACOT9.1 appears to play a role in fatty acid metabolism and energy production, therefore, it has been studied as a potential target for the treatment of metabolic disorders such as obesity and diabetes. However, more research is needed to determine if ACOT9.1-based therapies could be effective in treating these diseases.

Can ACOT9.1 protein be used as a biomarker for metabolic disorders?

ACOT9.1 protein has been suggested as a potential biomarker for metabolic disorders due to its involvement in lipid metabolism and its altered expression in these conditions. However, more studies are needed to establish the reliability and validity of ACOT9.1 as a biomarker for diagnosing or monitoring metabolic disorders.

Can ACOT9.1 protein be used for gene therapy?

ACOT9.1 protein is unlikely to be used for gene therapy as it is a naturally occurring protein in the human body and gene therapy typically involves the introduction of foreign genes into cells. However, the regulation of ACOT9.1 expression or activity using genetic manipulation techniques such as CRISPR-Cas9 may hold potential therapeutic benefits for metabolic disorders.

Is ACOT9.1 protein being used in clinical trials?

To our knowledge, ACOT9.1 protein is not currently being used in clinical trials. However, preclinical studies have shown promising results for ACOT9.1 inhibition in animal models of metabolic disorders.

Can ACOT9.1 protein be used for developing diagnostic tests?

ACOT9.1 protein may hold potential for developing diagnostic tests for metabolic disorders as its altered expression and activity has been linked to these conditions. However, more studies are needed to establish the reliability and validity of ACOT9.1 as a diagnostic marker.

How can ACOT9.1 protein be applied in drug development?

ACOT9.1 protein is a potential target for drug development as it plays a crucial role in lipid metabolism and its inhibition has been shown to improve insulin sensitivity and glucose homeostasis in animal models. Small molecule inhibitors that target ACOT9.1 may hold promise as therapeutics for metabolic disorders such as obesity and type 2 diabetes mellitus.

How is ACOT9.1 protein regulated?

The regulation of ACOT9.1 protein expression and activity is not yet fully understood. However, studies have suggested that its expression can be modulated by various factors such as diet, hormones, and genetic factors. ACOT9.1 activity can also be regulated by post-translational modifications such as phosphorylation and acetylation.

What are the challenges in developing therapies targeting ACOT9.1 protein?

Developing therapies targeting ACOT9.1 protein may face several challenges such as specificity of targeting, toxic effects, and off-target effects. Additionally, understanding the complex regulatory mechanisms of ACOT9.1 expression and activity is crucial for developing effective therapies. Further studies are needed to address these challenges and to develop safe and effective therapies targeting ACOT9.1 for metabolic disorders.

Can ACOT9.1 protein be targeted by dietary interventions?

The activity and expression of ACOT9.1 protein can be modulated by dietary factors such as fatty acids and omega-3 polyunsaturated fatty acids. Studies have demonstrated that dietary supplementation with omega-3 polyunsaturated fatty acids can reduce the expression of ACOT9.1 and improve insulin sensitivity and glucose homeostasis in animal models. Therefore, dietary interventions may hold promise in modulating ACOT9.1 activity as a potential therapeutic strategy for metabolic disorders.

Is the expression of ACOT9.1 protein altered in metabolic disorders?

The expression of ACOT9.1 protein has been shown to be altered in various metabolic disorders such as obesity, insulin resistance, and type 2 diabetes mellitus. Studies have demonstrated that the expression of ACOT9.1 is increased in adipose tissue of obese mice and humans, and that its inhibition can improve insulin sensitivity and glucose homeostasis.

Can ACOT9.1 protein be used in personalized medicine?

Personalized medicine involves tailoring treatments to an individual's genetic makeup, lifestyle, and other factors. ACOT9.1 protein may be useful in personalized medicine as its expression and activity can be modulated by various factors such as diet and genetic factors. This suggests that individuals with specific genetic variations or dietary habits may benefit from personalized treatments targeting ACOT9.1.