Recombinant Zebrafish ACSS2L

• Cat.No.: ACSS2L-8293Z
• Product Overview: Recombinant Zebrafish ACSS2L full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: acss2l acyl-CoA synthetase short-chain family member 2 like [ Danio rerio (zebrafish) ]
• Official Symbol: ACSS2L
• Gene ID: 560020
• mRNA Refseq: NM_001277117
• Protein Refseq: NP_001264046
• UniProt ID: A1L2B5

Reviews

08/08/2022

The efficacy and specificity of this protein are praiseworthy.

03/05/2021

Thumbs up for such a great product!

12/19/2020

The activity of this protein is remarkable. It shows robust enzymatic function, allowing precise and efficient catalysis in our biochemical assays.

07/23/2019

I'm highly impressed with the performance of this protein. It delivered consistent and reproducible results, allowing us to generate high-quality data.

10/14/2018

Working with this protein has been a delight. Its exceptional solubility and ease of handling have simplified our experimental workflows.

Q&As

How is ACSS2L protein expression regulated?

ACSS2L protein expression is regulated by alternative splicing of the ACSS2 pre-mRNA. The inclusion or exclusion of certain exons in the pre-mRNA determines the production of ACSS2L or other ACSS2 splice variants.

What is the genomic organization of the ACSS2 gene and its splicing variants?

The ACSS2 gene is located on human chromosome 20 and comprises 15 exons. Alternative splicing of the ACSS2 pre-mRNA generates several splice variants, including ACSS2L.

What is the effect of ACSS2L on cellular redox homeostasis?

ACSS2L may play a role in the regulation of cellular redox homeostasis, the balance between oxidants and antioxidants in the cell. ACSS2L may modulate cellular redox homeostasis by regulating the activity of the Nrf2 pathway, a transcription factor that regulates the expression of genes involved in antioxidant defense.

What is the relationship between ACSS2L and cellular iron metabolism?

ACSS2L may play a role in the regulation of cellular iron metabolism by modulating the activity of the iron regulatory protein (IRP) pathway, which controls the expression of genes involved in iron uptake, storage, and utilization.

What is the effect of ACSS2L on cellular stress response and apoptosis?

ACSS2L may play a role in the cellular stress response and apoptosis by regulating the activity of the protein kinase Akt and the transcription factor FOXO3a, which are involved in cell survival and death.

What is the relationship between ACSS2L and acetylation of the transcription factor p53?

ACSS2L may play a role in the acetylation of the transcription factor p53, a key regulator of cell cycle arrest and apoptosis in response to cellular stress.

What is the molecular mechanism by which ACSS2L regulates gene expression?

ACSS2L may regulate gene expression by modulating the activity of histone deacetylases (HDACs), which are enzymes that control chromatin structure and gene transcription.

What is the effect of ACSS2L overexpression on lipid metabolism in cells?

Overexpression of ACSS2L in cells leads to an increase in lipid droplet accumulation and fatty acid synthesis, suggesting that ACSS2L may play a role in lipid metabolism.

What is the relationship between ACSS2L and the AMP-activated protein kinase (AMPK) pathway?

ACSS2L protein may be involved in the regulation of the AMPK pathway, a cellular energy sensor that regulates metabolism in response to changes in cellular energy status.

What is the effect of ACSS2L knockdown on cell proliferation?

knockdown of ACSS2L expression in cancer cells leads to a decrease in cell proliferation and viability, suggesting that ACSS2L may play a role in cancer cell survival.