Recombinant Zebrafish AGO4

• Cat.No.: AGO4-8105Z
• Product Overview: Recombinant Zebrafish AGO4 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: ago4 argonaute RISC catalytic component 4 [ Danio rerio (zebrafish) ]
• Official Symbol: AGO4
• Gene ID: 100535764
• mRNA Refseq: NM_001252559
• Protein Refseq: NP_001239488
• UniProt ID: K4IAH1

Reviews

03/25/2021

 The cost-effectiveness of the product, coupled with clear instructions, was advantageous.

10/17/2020

 The protein product’s innovative features enabled exploration of novel cellular mechanisms.

10/27/2019

 Consistently obtaining specific outcomes with the protein product validated its importance.

09/25/2018

 Despite its price, the product’s contributions to our research goals made it invaluable.

07/07/2016

 The product consistently met our expectations, lending credibility to our findings.

Q&As

How does AGO4’s role relate to small RNA-directed DNA methylation

AGO4 guides small RNAs to DNA targets for methylation.

How is AGO4’s function studied in RNA silencing

Research explores AGO4’s role in guiding small RNAs to target sequences for DNA methylation.

Can AGO4 influence gene expression

Yes, AGO4’s activity leads to the suppression of gene expression through DNA methylation.

How does AGO4’s function affect chromatin structure

AGO4’s role in gene silencing contributes to the modulation of chromatin structure.

How does AGO4’s function impact transgenerational epigenetic inheritance

AGO4’s role in DNA methylation can influence epigenetic inheritance.

How does AGO4’s activity relate to heterochromatin formation

AGO4 participates in heterochromatin formation through gene silencing.

How does AGO4 interact with small RNAs

AGO4 interacts with small RNAs, including small interfering RNAs and long non-coding RNAs.

Can AGO4’s activity influence cell differentiation

Yes, AGO4’s function can impact cell differentiation and developmental pathways.

Can AGO4’s activity be involved in epigenetic regulation

Yes, AGO4’s role includes epigenetic regulation through RNA-directed DNA methylation.

Can AGO4 be involved in stress responses

Yes, AGO4’s activity can be modulated by cellular stress and environmental changes.

How is AGO4’s role connected to DNA methylation

AGO4 guides small RNAs to complementary DNA sequences, leading to DNA methylation.

Is AGO4 essential for normal development

Yes, AGO4 is essential for normal development and epigenetic regulation.

Is AGO4’s role conserved among different species

Research explores whether AGO4’s function is conserved across various organisms.

Can AGO4 be targeted for therapeutic interventions

Yes, AGO4 is a potential target for modulating gene expression and treating diseases.

Can AGO4 regulate gene expression at transcriptional level

Yes, AGO4’s role includes transcriptional gene silencing through DNA methylation.

How is AGO4’s dysfunction linked to diseases

AGO4 dysfunction can be linked to disorders involving aberrant gene regulation.

Can AGO4’s activity regulate developmental processes

Yes, AGO4’s function impacts developmental processes through gene regulation.

Can AGO4’s involvement extend to plant biology studies

Yes, AGO4’s role in RNA interference is studied in plant biology contexts.

How is AGO4’s interaction with target DNA studied

Research investigates how AGO4 recognizes and interacts with specific DNA sequences.

How is AGO4’s connection to epitranscriptomics studied

Research explores AGO4’s possible links to epitranscriptomic modifications.

Is AGO4’s activity influenced by post-translational modifications

Yes, post-translational modifications might affect AGO4’s function.

How does AGO4’s role contribute to epigenetic memory

AGO4’s involvement in DNA methylation helps maintain epigenetic memory across generations.

Can AGO4’s function impact transposon silencing

Yes, AGO4 is involved in silencing transposable elements and maintaining genome stability.