Recombinant Zebrafish AGXTB
Cat.No. : | AGXTB-12378Z |
Product Overview : | Recombinant Zebrafish AGXTB full length or partial length protein was expressed. |
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Source : | Mammalian Cells |
Species : | Zebrafish |
Tag : | His |
Form : | Liquid or lyophilized powder |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >80% |
Notes : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Storage : | Store it at +4 oC for short term. For long term storage, store it at -20 oC~-80 oC. |
Storage Buffer : | PBS buffer |
Gene Name : | agxtb alanine-glyoxylate aminotransferase b [ Danio rerio (zebrafish) ] |
Official Symbol : | AGXTB |
Gene ID : | 79378 |
mRNA Refseq : | NM_213162 |
Protein Refseq : | NP_998327 |
UniProt ID : | Q6PHK4 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAGXTB is crucial in maintaining glyoxylate homeostasis, preventing the accumulation of glyoxylate that could lead to oxalate formation and calcium oxalate-related kidney stone disease.
AGXTB's expression and function may vary among different tissues, contributing to organ-specific metabolic adaptations and responses.
Yes, AGXTB may play a role in regulating glyoxylate production in response to certain physiological conditions, such as oxidative stress or changes in amino acid metabolism.
AGXTB deficiency itself is not associated with PH1; however, perturbations in AGXTB function may indirectly impact PH1 development by influencing glyoxylate levels.
Yes, certain genetic variations in the AGXTB gene have been linked to an increased risk of developing calcium oxalate kidney stones in some populations.
AGXTB has been implicated in cellular redox balance, as glyoxylate metabolism can influence cellular reactive oxygen species (ROS) levels, affecting oxidative stress.
Yes, certain dietary factors, such as vitamin B6 deficiency, have been shown to affect AGXTB activity, leading to perturbations in glyoxylate metabolism and kidney stone formation.
The transcriptional regulation of AGXTB involves various factors, including peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and hepatocyte nuclear factor 4-alpha (HNF-4α), which bind to specific regulatory regions of the AGXT2L1 gene.
AGXTB collaborates with other enzymes, such as alanine-glyoxylate aminotransferase (AGXT), to maintain the balance between glyoxylate and glycine levels, which is essential in mitigating the risk of kidney stone formation.
AGXTB, as an aminotransferase, participates in the interconversion of other amino acids, such as serine, alanine, and aspartate, in addition to its role in the glyoxylate-glycine pathway.
Customer Reviews (5)
Write a reviewThe customer support was also excellent, providing prompt assistance when needed.
If you want top-notch results, this protein is the way to go!
Excellent value for its price
The customer service was exceptional, with prompt assistance and valuable technical support.
I would appreciate more detailed documentation accompanying the product.
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