AGXTB
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | AGXTB-12378Z | Recombinant Zebrafish AGXTB | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
AGXTB involved in several pathways and played different roles in them. We selected most pathways AGXTB participated on our site, such as Alanine, aspartate and glutamate metabolism, Glycine, serine and threonine metabolism, Glyoxylate and dicarboxylate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGXTB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alanine, aspartate and glutamate metabolism | ADSL;CAD;GOT2;GAD1B;GOT2A;AGXTB;AGXT;GLSA;GLS2 |
| Glycine, serine and threonine metabolism | GCSH;GLYCTK;GNMT;PGAM1B;DAO.3;PGAM1;SRR;PSPH;DAO.1 |
| Glyoxylate and dicarboxylate metabolism | GRHPRB;GCSHA;GCSH;ANI_1_2390104;ACAT2;HAO1;AFMID;SHMT2;GLULC |
| Metabolic pathways | PLCH1;HSD3B7;Atp5k;MTAP;CYP2A4;AGPAT5;GALCA;ASS1;SPRA |
| Carbon metabolism | GPIB;CS;HAO1;TKT;GOT2A;ACSS1;PHGDH;FBP2;ENO1B |
| Peroxisome | ABCD1;ANI_1_2390104;CRATB;ACSL4;AGXTA;ACOX2;ACSL4B;ACSL1;ACSL5 |
AGXTB has several biochemical functions, for example, alanine-glyoxylate transaminase activity, catalytic activity, serine-pyruvate transaminase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AGXTB itself. We selected most functions AGXTB had, and list some proteins which have the same functions with AGXTB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alanine-glyoxylate transaminase activity | AGXT;AGXT2;AGXTA;AGXTB |
| catalytic activity | PPM1AA;LGI1A;PGAM1;ODZ4;TDH2;ALPI.1;UQCRC2B;PDXDC1;LYZ2 |
| serine-pyruvate transaminase activity | AGXTA;AGXT;AGXTB |
| transaminase activity | AGXTB;AGXT;GOT1L1;CCBL1;ETNPPL;AGXT2;AGXT2L2;AGXTA;AGXT2L1 |
| transferase activity | HECTD1;B3GNTL1;BMPR1AA;SULT2ST2;MAPK8B;CTU1;AK5L;GLT8D1;ERBB3B |
AGXTB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGXTB here. Most of them are supplied by our site. Hope this information will be useful for your research of AGXTB.
- Q&As
- Reviews
Q&As (10)
Ask a questionAGXTB is crucial in maintaining glyoxylate homeostasis, preventing the accumulation of glyoxylate that could lead to oxalate formation and calcium oxalate-related kidney stone disease.
AGXTB's expression and function may vary among different tissues, contributing to organ-specific metabolic adaptations and responses.
Yes, AGXTB may play a role in regulating glyoxylate production in response to certain physiological conditions, such as oxidative stress or changes in amino acid metabolism.
AGXTB deficiency itself is not associated with PH1; however, perturbations in AGXTB function may indirectly impact PH1 development by influencing glyoxylate levels.
Yes, certain genetic variations in the AGXTB gene have been linked to an increased risk of developing calcium oxalate kidney stones in some populations.
AGXTB has been implicated in cellular redox balance, as glyoxylate metabolism can influence cellular reactive oxygen species (ROS) levels, affecting oxidative stress.
Yes, certain dietary factors, such as vitamin B6 deficiency, have been shown to affect AGXTB activity, leading to perturbations in glyoxylate metabolism and kidney stone formation.
The transcriptional regulation of AGXTB involves various factors, including peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and hepatocyte nuclear factor 4-alpha (HNF-4α), which bind to specific regulatory regions of the AGXT2L1 gene.
AGXTB collaborates with other enzymes, such as alanine-glyoxylate aminotransferase (AGXT), to maintain the balance between glyoxylate and glycine levels, which is essential in mitigating the risk of kidney stone formation.
AGXTB, as an aminotransferase, participates in the interconversion of other amino acids, such as serine, alanine, and aspartate, in addition to its role in the glyoxylate-glycine pathway.
Customer Reviews (5)
Write a reviewThe customer support was also excellent, providing prompt assistance when needed.
If you want top-notch results, this protein is the way to go!
Excellent value for its price
The customer service was exceptional, with prompt assistance and valuable technical support.
I would appreciate more detailed documentation accompanying the product.
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