Recombinant Zebrafish ALX4B

• Cat.No.: ALX4B-5512Z
• Product Overview: Recombinant Zebrafish ALX4B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: alx4b ALX homeobox 4b [ Danio rerio (zebrafish) ]
• Official Symbol: ALX4B
• Gene ID: 497424
• mRNA Refseq: NM_001089357
• Protein Refseq: NP_001082826
• UniProt ID: A4IGC5

Reviews

06/17/2021

Enhanced reproducibility in protein expression studies.

02/29/2020

Low reagent consumption for cost-effective experiments.

02/14/2020

Efficient detection of protein degradation or turnover.

Q&As

What are the signaling pathways that regulate the expression or activity of ALX4B, and how does it integrate with these pathways to modulate cellular responses?

ALX4B is regulated by various signaling pathways, including Wnt, BMP, or Notch signaling, which can modulate its expression or activity to influence cellular responses.

How does ALX4B contribute to embryonic development, and what are the phenotypic consequences of its loss-of-function or gain-of-function mutations?

Loss-of-function or gain-of-function mutations in ALX4B can lead to developmental defects, impaired tissue homeostasis, or disease phenotypes, depending on the specific context.

How does ALX4B contribute to disease pathogenesis, and what are the potential therapeutic strategies targeting ALX4B for the treatment of related disorders?

Dysregulation of ALX4B has been implicated in certain diseases, such as craniofacial disorders or skeletal anomalies, highlighting its potential as a therapeutic target for related conditions.

What are the interacting partners of ALX4B, and how do these interactions modulate its activity and downstream signaling pathways?

ALX4B interacts with transcriptional co-regulators, chromatin modifiers, or DNA binding proteins to modulate its transcriptional activity and downstream signaling pathways.

What are the structural features of ALX4B that are critical for its function, and how do they contribute to its DNA binding or protein-protein interaction capabilities?

The specific domains or motifs within ALX4B, such as the homeodomain or transcription activation/repression domains, are critical for its DNA binding, protein-protein interactions, or transcriptional regulation.

Can ALX4B be used as a diagnostic or prognostic marker for specific diseases, and what are the implications for patient stratification or personalized medicine?

ALX4B expression levels or genetic variants may serve as diagnostic or prognostic markers for specific diseases, providing insights into disease mechanisms or predicting treatment responses in individual patients.

What are the molecular mechanisms underlying the regulatory role of ALX4B in tissue regeneration, repair, or wound healing?

ALX4B plays a role in tissue regeneration, repair, or wound healing by regulating cellular processes such as proliferation, migration, or extracellular matrix remodeling.

What are the post-translational modifications of ALX4B, and how do they regulate its stability, activity, or protein-protein interactions?

ALX4B undergoes post-translational modifications, including phosphorylation or acetylation, which can regulate its stability, activity, or protein-protein interactions.

What are the downstream target genes regulated by ALX4B, and what are their roles in cellular processes such as development, differentiation, or tissue homeostasis?

ALX4B regulates the expression of genes involved in developmental processes, tissue homeostasis, or cellular differentiation, such as those encoding transcription factors, growth factors, or extracellular matrix components.

What is the subcellular localization of ALX4B in different cell types, and how does it contribute to its function in cellular processes?

ALX4B exhibits a predominantly nuclear localization in various cell types, indicating its involvement in transcriptional regulation.