Recombinant Zebrafish ARRDC3A

• Cat.No.: ARRDC3A-4978Z
• Product Overview: Recombinant Zebrafish ARRDC3A full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: arrdc3a arrestin domain containing 3a [ Danio rerio (zebrafish) ]
• Official Symbol: ARRDC3A
• Gene ID: 566685
• mRNA Refseq: NM_001080029
• Protein Refseq: NP_001073498
• UniProt ID: Q1ECU3

Reviews

12/20/2020

The manufacturer's prompt and reliable technical support serves as an invaluable resource, reinforcing my confidence in the ARRDC3A protein's effectiveness and enabling smooth progress in my experiments.

04/19/2018

The combination of the protein's excellence and the manufacturer's exceptional technical support equips me with the necessary resources to overcome experimental obstacles and achieve groundbreaking results.

06/20/2016

I am eager to embark on this scientific journey, empowered by the high-quality ARRDC3A protein and the manufacturer's unparalleled assistance.

Q&As

Is ARRDC3A tissue-specific, or is it expressed in multiple tissues?

ARRDC3A is expressed in various tissues, including the brain, heart, lung, liver, and kidney. Its expression pattern suggests its involvement in multiple physiological processes throughout the body.

Are there any known interactions of ARRDC3A with other proteins?

Yes, ARRDC3A has been reported to interact with several proteins. For example, it interacts with the G protein-coupled receptor kinases (GRKs) and β-arrestins, suggesting a potential involvement in the regulation of G protein-coupled receptor (GPCR) signaling.

Does ARRDC3A have any implications in disease or pathology?

The role of ARRDC3A in disease or pathology is not extensively studied. However, some studies have suggested its involvement in cancer progression and metastasis. Further research is needed to fully understand its contribution to disease processes.

Does ARRDC3A have any known subcellular localization?

ARRDC3A has been found to localize to different compartments within cells, including the plasma membrane and endosomes. Its localization may vary depending on the cellular context and specific signaling pathways it is involved in.

Is ARRDC3A involved in any cellular pathways or signaling cascades?

ARRDC3A is believed to participate in various cellular pathways. It has been implicated in the Notch signaling pathway, which is important for cell fate determination and development. Additionally, ARRDC3A may be involved in modulating the Wnt signaling pathway, which regulates various cellular processes such as cell proliferation and differentiation.

Are there any known genetic variants or mutations in the ARRDC3A gene?

Currently, there is limited information regarding specific genetic variants or mutations in the ARRDC3A gene. Further research is needed to explore if any genetic alterations in ARRDC3A contribute to diseases or phenotypic variations.

Are there any known post-translational modifications of ARRDC3A?

Currently, there is limited information on post-translational modifications of ARRDC3A. However, phosphorylation has been shown to regulate the protein stability and function of other members of the ARRDC protein family. It would be interesting to investigate if ARRDC3A undergoes similar modifications.