Recombinant Zebrafish ASAH2

• Cat.No.: ASAH2-1839Z
• Product Overview: Recombinant Zebrafish ASAH2 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: asah2 N-acylsphingosine amidohydrolase 2 [ Danio rerio (zebrafish) ]
• Official Symbol: ASAH2
• Gene ID: 493602
• mRNA Refseq: NM_001007763
• Protein Refseq: NP_001007764
• UniProt ID: Q5W7F1

Reviews

04/04/2019

It reliably and accurately detects and quantifies target molecules, allowing for precise measurement of analytes in my samples.

02/25/2019

I highly recommend the ASAH2 Protein for its outstanding performance in ELISA assays.

11/22/2016

The sensitivity and specificity of the ASAH2 Protein have consistently delivered robust and consistent results, enhancing the efficiency and accuracy of my experimental workflows.

Q&As

Can ASAH2 activity be regulated by post-translational modifications?

Post-translational modifications, such as phosphorylation, may impact ASAH2 activity, although further research is needed for a comprehensive understanding.

Are there any known inhibitors of ASAH2?

While specific inhibitors for ASAH2 are not yet available, researchers are actively exploring potential compounds that can modulate its activity.

In which cellular compartments is ASAH2 found?

ASAH2 is primarily localized in the lysosomes, where it carries out the ceramide hydrolysis process.

What are the consequences of ASAH2 deficiency?

Deficiency in ASAH2 activity can lead to the accumulation of ceramides, which may disrupt cellular signaling and contribute to disease development.

How is ASAH2 gene expression regulated?

ASAH2 gene expression can be regulated by various factors, including transcription factors, epigenetic modifications, and signaling pathways.

Are there any diseases associated with ASAH2?

Mutations in the ASAH2 gene have been associated with a rare form of hereditary sensory and autonomic neuropathy (HSAN) called HSAN1C.

Is ASAH2 ubiquitously expressed in all tissues?

Yes, ASAH2 is ubiquitously expressed in various tissues throughout the body.