Recombinant Zebrafish ASAP2A

• Cat.No.: ASAP2A-4228Z
• Product Overview: Recombinant Zebrafish ASAP2A full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: asap2a ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a [ Danio rerio (zebrafish) ]
• Official Symbol: ASAP2A
• Gene ID: 570669
• mRNA Refseq: NM_001045207
• Protein Refseq: NP_001038672
• UniProt ID: Q5RG20

Reviews

04/17/2019

ASAP2A protein is known for its versatility and functionality, enabling researchers to explore various biological processes and molecular interactions.

11/07/2017

Its purity and reliability ensure reliable and reproducible results in a variety of research applications.

01/28/2017

Whether I need expertise in experimental optimization or troubleshooting, I can rely on the manufacturer's support to promptly address any concerns or queries.

Q&As

Does ASAP2A play a role in neuronal processes?

ASAP2A has been reported to be involved in neuronal dendritic spine formation and synaptic plasticity, suggesting a role in neuronal processes.

Is ASAP2A involved in cancer progression?

ASAP2A has been implicated in cancer metastasis due to its ability to promote cell migration and invasion through its effect on the actin cytoskeleton.

Are ASAP2 and ASAP2A the same protein?

ASAP2A is one isoform of the ASAP2 protein, with ASAP2B being another isoform.

Can ASAP2A be regulated by post-translational modifications?

Yes, ASAP2A can undergo phosphorylation and ubiquitination, which may influence its stability, activity, and protein-protein interactions.

How does ASAP2A regulate membrane trafficking?

ASAP2A promotes the hydrolysis of GTP bound to Arf1, leading to the inactivation of Arf1 and subsequent modulation of vesicle budding, cargo sorting, and membrane remodeling.

Can ASAP2A interact with other proteins?

Yes, ASAP2A can interact with various proteins involved in membrane trafficking, including clathrin, AP1, AP3, and many others.

Are there any genetic variations associated with ASAP2A?

Genetic variations in ASAP2A have been identified in some studies, and they may be linked to certain diseases or phenotypes, although more research is needed to establish concrete associations.

Does ASAP2A play a role in cell adhesion?

Yes, ASAP2A has been suggested to modulate cell adhesion and migration by regulating actin cytoskeleton dynamics through its interaction with Rho family GTPases.