Recombinant Zebrafish ASAP2B

• Cat.No.: ASAP2B-4034Z
• Product Overview: Recombinant Zebrafish ASAP2B full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Zebrafish
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 oC for short term. For long term storage, store it at -20 oC～-80 oC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: asap2b ArfGAP with SH3 domain, ankyrin repeat and PH domain 2b [ Danio rerio (zebrafish) ]
• Official Symbol: ASAP2B
• Gene ID: 560581
• mRNA Refseq: NM_001044933
• Protein Refseq: NP_001038398
• UniProt ID: A1L1T9

Reviews

08/06/2021

The ASAP2B protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.

06/03/2021

the manufacturer of ASAP2B provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.

11/25/2018

Its high quality greatly enhances the reliability and reproducibility of experimental data.

Q&As

Are there any genetic variations associated with ASAP2B?

Genetic variations in ASAP2B have been identified in some studies, and they may be linked to certain diseases or phenotypes, although more research is needed to establish concrete associations.

Where is ASAP2B primarily localized within cells?

ASAP2B is found in the cytoplasm, associated with cellular membranes, particularly the Golgi apparatus and endosomes.

Is ASAP2B involved in cancer progression?

ASAP2B has been implicated in cancer metastasis due to its ability to promote cell migration and invasion through its effect on the actin cytoskeleton.

Does ASAP2B play a role in cell adhesion?

Yes, ASAP2B has been suggested to modulate cell adhesion and migration by regulating actin cytoskeleton dynamics through its interaction with Rho family GTPases.

Can ASAP2B be regulated by post-translational modifications?

Yes, ASAP2B can undergo phosphorylation and ubiquitination, which may influence its stability, activity, and protein-protein interactions.

Can ASAP2B interact with other proteins?

Yes, ASAP2B can interact with various proteins involved in membrane trafficking, including clathrin, AP1, AP3, and many others.

Is ASAP2B similar to ASAP2A?

Yes, ASAP2B is another isoform of the ASAP2 protein, with ASAP2A being the other isoform.

How does ASAP2B regulate membrane trafficking?

ASAP2B promotes the hydrolysis of GTP bound to Arf1, leading to the inactivation of Arf1 and subsequent modulation of vesicle budding, cargo sorting, and membrane remodeling.