DLL4
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Official Full Name
delta-like 4 (Drosophila)
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Overview
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008] -
Synonyms
DLL4; delta-like 4 (Drosophila); hdelta2; delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Antibody
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- CHO cells
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- Fc
- Avi
- GST
- hFc
- His
- His (Fc)
- His|GST
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- DLL4 Related Articles
- DLL4 Related Research Area
DLL4 involved in several pathways and played different roles in them. We selected most pathways DLL4 participated on our site, such as Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Notch signaling pathway | LNX1;MARK2;HER12;DTX4;NOTCH4;APH1B;ADAM17;NUMB;DLK1 |
DLL4 has several biochemical functions, for example, Notch binding, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLL4 itself. We selected most functions DLL4 had, and list some proteins which have the same functions with DLL4. You can find most of the proteins on our site.
Function | Related Protein |
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Notch binding | AAK1;JAG1;SNW1;DNER;ADAM17;NOTCH1;NOTCH4;EGFL7;C8orf4 |
calcium ion binding | PLCD1B;CETN4;LCP1;DLC;CALM4;EHD1A;EFCAB4A;ITSN2;LTBP3 |
protein binding | TMEM120B;pab1;Serpina1b;RIPK4;ATF6B;TIA1;ERBB2;PCBP2;PRDM16 |
DLL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLL4.
- Q&As
- Reviews
Q&As (5)
Ask a questionDLL4 is implicated in the regulation of vascular inflammation and plaque formation, making it a potential target for atherosclerosis treatments.
DLL4 has been linked to Alzheimer's disease as it can influence amyloid-beta accumulation and the activation of microglia in the brain.
DLL4 levels can serve as a potential biomarker in some diseases, such as certain cancers, where it may indicate disease progression.
Challenges include potential side effects, the need for personalized treatment approaches, and the complexity of the Notch signaling pathway.
DLL4 can modulate tissue regeneration by influencing stem cell behavior and promoting tissue repair processes.
Customer Reviews (3)
Write a reviewThey ensure a consistent and reliable supply of DLL4 protein, minimizing any potential disruptions in my experimental workflow.
the manufacturer's commitment to scientific collaboration and knowledge sharing greatly enhances my research experience.
This collaborative approach empowers me to integrate cutting-edge knowledge, explore innovative techniques, and expand the impact of my research.
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