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EPHB4

  • Official Full Name

    EPH receptor B4

  • Overview

    Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to
  • Synonyms

    EPHB4; EPH receptor B4; EphB4 , HTK; ephrin type-B receptor 4; Tyro11; ephrin receptor EphB4; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; hepatoma transmembrane kinase; tyrosine-protein kinase TYRO11; tyrosine-protein kinase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian cells
  • Mouse
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • DDK|His
  • Fc
  • Fc|His
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • MYC
  • Myc|DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EPHB4-231H Recombinant Human EPHB4, C13&N15-labeled HEK293 N/A
Human EPHB4-379H Recombinant Human EPHB4 Protein, DDK-tagged Insect Cell DDK Met-Leu16-Ala539
Human EPHB4-378H Recombinant Human EPHB4 Protein, DDK/His-tagged HEK293 DDK/His Leu16 – Leu539
Human EPHB4-306H Recombinant Human EPH Receptor B4, GST-tagged, Active Sf9 Insect Cell GST
Human EPHB4-695H Recombinant Human EPHB4, Fc tagged Human Cell Fc
Human EPHB4-697H Recombinant Human EPHB4, None tagged Human Cell N/A
Human EPHB4-356H Recombinant Human EPHB4 protein, His-tagged, Biotinylated HEK293 His Leu 16 - Ala 539
Human EPHB4-543H Recombinant Human EPH Receptor B4, His-tagged Sf9 Insect Cell His
Human EPHB4-3403H Active Recombinant Human EPHB4 Protein, GST-tagged Insect Cell GST
Human EPHB4-28623TH Recombinant Human EPHB4 N/A
Human EPHB4-3404H Recombinant Human EPHB4 Protein, GST-tagged Wheat Germ GST
Human EPHB4-12495H Recombinant Human EPHB4, GST-tagged E.coli GST 639-987a.a.
Human EPHB4-7278H Active Recombinant Human EPHB4 protein, His&GST-tagged Insect Cells His/GST Leu563-Tyr987
Human EPHB4-696H Recombinant Human EPHB4 protein, His-tagged HEK293 His Glu17-Ala539
Human EPHB4-28580TH Recombinant Human EPHB4, His-tagged His
Human EPHB4-4762H Recombinant Human EPH Receptor B4, His-tagged HEK293 His
Human EPHB4-2970HCL Recombinant Human EPHB4 cell lysate Human Cell N/A
Human EPHB4-001HCL Recombinant Human EPHB4 cell lysate Insect Cell N/A
Human EPHB4-003H Recombinant Human EPHB4 Protein, His-tagged Insect Cell His
Human CAB11531MH Mouse Anti-Human EPH Receptor B4 Monoclonal Antibody Mouse N/A
Human EPHB4-0416H Recombinant Human EPHB4 protein, His-tagged E.coli His 639-987 aa
Human EPHB4-363H Recombinant Human EPHB4 Protein (Met1-Ala539), His-tagged, Biotinylated Insect Cell His Met1-Ala539
Human EPHB4-4382HF Recombinant Full Length Human EPHB4 Protein, GST-tagged In Vitro Cell Free System GST 987 amino acids
Human EPHB4-853H-B Recombinant Human EPHB4 Protein Pre-coupled Magnetic Beads HEK293
Human EphB4-1949H Recombinant Human EphB4 protein, His-tagged HEK293 His Leu 16 - Ala 539
Human EPHB4-4943H Recombinant Human EPHB4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EPHB4-0993H Recombinant Human EPHB4 Protein (E17-K196), Tag Free Insect Cell No tag E17-K196
Human EPHB4-1898H Recombinant Human EPHB4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human EPHB4-853H Recombinant Human EPHB4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human EPHB4-364H Recombinant Human EPHB4 protein, GST-tagged E. coli GST 197-539 aa
Human EPHB4-0994H Recombinant Human EPHB4 Protein (E17-K196), His tagged Insect Cell His E17-K196
Human EPHB4-3274H Recombinant Human EPHB4 Protein (Leu16-Ala539), N-His tagged E.coli N-His Leu16-Ala539
Human EPHB4-227H Recombinant Human EPHB4 Protein, His-tagged, Biotinylated HEK293 His 987
Human EPHB4-1774HFL Recombinant Full Length Human EPHB4 Protein, C-Flag-tagged Mammalian cells Flag
Human EPHB4-228H Recombinant Human EPHB4 Protein, His-tagged HEK293 His 987
Mouse Ephb4-4053M Active Recombinant Mouse Ephb4 protein, His-tagged HEK293 His Met1-Ala539
Mouse Ephb4-1729M Recombinant Mouse Eph Receptor B4, Fc-His Mammalian cells Fc/His
Mouse Ephb4-4052M Recombinant Mouse Ephb4, Fc tagged Human Cell Fc
Mouse EPHB4-2128MCL Recombinant Mouse EPHB4 cell lysate Human Cell N/A
Mouse Ephb4-161M Recombinant Mouse Ephb4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ephb4-958M Recombinant Mouse Ephb4 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Ephb4-161M-B Recombinant Mouse Ephb4 Protein Pre-coupled Magnetic Beads HEK293
Kit-1548 U2OS EphB4 Bioassay Kit N/A
Kit-1585 EphB4 Functional Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EPHB4 Related Articles

EPHB4 involved in several pathways and played different roles in them. We selected most pathways EPHB4 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with EPHB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceGFRA4;COL4A3;EZRA;NRG2A;RAC1;CLTB;CSNK2A2;KALRN;SEMA6B

EPHB4 has several biochemical functions, for example, ATP binding, ephrin receptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EPHB4 itself. We selected most functions EPHB4 had, and list some proteins which have the same functions with EPHB4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMAST2;UCK2;ATP6AP1;RECQL;MAP3K12;HSPA8;IRAK1;ITPK1;MAP2K7
ephrin receptor activityEPHA10;EPHA4B;EPHB4B;EPHA6;EPHA5;EPHB3A;EPHB2B;EK1;EPHA2
protein bindingMID1IP1;SNX20;NAIF1;RINL;DHX38;ELOVL6;PODXL;MYCBP2;SUZ12
transmembrane receptor protein tyrosine kinase activityROR2;EPHA4A;RET;NTRK1;DDR2;KITB;FGFR1A;INSRB;NTRK3

EPHB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EPHB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of EPHB4.

bosutinib; dasatinib; saicar; ephopt; PKM; abl-tide; JUN; linkable pd173955 analogue; linkable vandetanib analogue; imatinib; purvalanol b; crizotinib; EGFR; ZSCAN5A; PARD6A; Skp1

Liu, SL; Li, D; et al. Design, Synthesis, and Validation of Axl-Targeted Monoclonal Antibody Probe for microPET Imaging in Human Lung Cancer Xenograft. MOLECULAR PHARMACEUTICS 11:3974-3979(2014).
Nagano, K; Maeda, Y; et al. Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers. JOURNAL OF CONTROLLED RELEASE 189:72-79(2014).
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