FOXP1
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Official Full Name
forkhead box P1
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Overview
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] -
Synonyms
FOXP1; forkhead box P1; QRF1; 12CC4; hFKH1B; HSPC215; forkhead box protein P1; glutamine-rich factor 1; fork head-related protein like B;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Insect Cell
- Mammalian Cell
- Wheat Germ
- DDK
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- MYC
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- FOXP1 Related Articles
- FOXP1 Related Research Area
FOXP1 involved in several pathways and played different roles in them. We selected most pathways FOXP1 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with FOXP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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MicroRNAs in cancer | HRAS;ZFPM2;CCND1;PRKCG;FZD3;ABCC1;NFKB1;PIM1;TP53 |
FOXP1 has several biochemical functions, for example, RNA polymerase II transcription factor activity, sequence-specific DNA binding, androgen receptor binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FOXP1 itself. We selected most functions FOXP1 had, and list some proteins which have the same functions with FOXP1. You can find most of the proteins on our site.
Function | Related Protein |
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RNA polymerase II transcription factor activity, sequence-specific DNA binding | FOXE3;TFAP2D;FLI1;SP3;MITFB;JUNBA;ZNF576;ELF3;ZSCAN1 |
androgen receptor binding | NSD1;CTNNB1;PRMT2;FOXP1;DAXX;RNF6;TCF21;FOXH1;PRPF6 |
metal ion binding | LIG1;GNPTAB;ARSG;ZFYVE28;GALNTL2;ZNF285A;CCDC76;RASSF5;LRP2 |
protein binding | CTNNBL1;LILRA4;UBE2V2;SART3;USP19;MOB4;PITPNM3;KHDRBS1;CD200R2 |
sequence-specific DNA binding | EN2;RXRBB;NFIL3-6;POU2F1;CUX2;FOXO4;LHX1A;HOXB8A;EVX2 |
FOXP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FOXP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FOXP1.
LRRK1; IL3RA; alaS; mglA3; q7cia4_yerpe; opuD; ppk; gabD; mdtB; arre2_element_mouse_il2_promoter; MYC
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