GHRH
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Official Full Name
Ghrh growth hormone releasing hormone
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Overview
The protein encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the;hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate;growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of;tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of;dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. -
Synonyms
GHRH; growth hormone releasing hormone; somatoliberin; GRF; growth hormone-releasing factor; growth hormone-releasing hormone; GHRF;
- Recombinant Proteins
- Native Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Sheep
- Zebrafish
- E.coli
- HEK293
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- Fc
- GST
- His
- His (Fc)
- Avi
- His|GST
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- GHRH Related Articles
GHRH involved in several pathways and played different roles in them. We selected most pathways GHRH participated on our site, such as Class B/2 (Secretin family receptors), G alpha (s) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GHRH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class B/2 (Secretin family receptors) | CALCRL;GNB3B;EMR4;EMR1;RAMP3;PTHLH;ADCYAP1R1;CALCA;ADM2A |
| G alpha (s) signalling events | CRHR1;PTHLHA;RLN2;CALCB;TAAR1;ADRB3;PDE10A;INSL3;RLN3A |
| GPCR downstream signaling | ADORA1;GCGA;RGS20;SOUL4;TAC3;PIK3R6;CCR9;DRD4;QRFPR |
| GPCR ligand binding | PYY;CXCR6;CRHB;KEL;RGR;OXTRL;S1PR3;NMU;ADORA3 |
| Signal Transduction | BCL9L;PYGO2;GPR132;PTH;OMG;CRABP2A;RGS11;ARHGAP29;CDH5 |
| Signaling by GPCR | OR2AP1;MLN;GPR18;TAC3;RGS11;OXGR1A.1;HCAR1-2;GPR39;EMR1 |
GHRH has several biochemical functions, for example, growth hormone-releasing hormone activity, growth hormone-releasing hormone receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GHRH itself. We selected most functions GHRH had, and list some proteins which have the same functions with GHRH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| growth hormone-releasing hormone activity | GHRH;GHRL |
| growth hormone-releasing hormone receptor binding |
GHRH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GHRH here. Most of them are supplied by our site. Hope this information will be useful for your research of GHRH.
DPP4; FAP
- Q&As
- Reviews
Q&As (5)
Ask a questionNo, it's also being explored for its potential in other conditions like muscle wasting diseases and cognitive disorders.
Effects on growth may take several months to become noticeable, depending on the individual and the underlying condition.
It stimulates the pituitary gland to release growth hormone, which regulates growth, metabolism, and body composition.
GHRH therapy is beneficial for children with growth hormone deficiencies and adults with certain growth hormone-related disorders.
Typically, it's used in children and adults with specific hormone deficiencies or growth-related conditions.
Customer Reviews (3)
Write a reviewGHRH is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.
One aspect that sets the GHRH Protein apart is the excellent technical support provided by the manufacturer.
I have found the GHRH Protein to be highly stable, enabling long-term experiments without compromising its performance.
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