GNAO1
-
Official Full Name
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
-
Overview
Gi alpha subunit (or Gi/G0 or Gi protein) is a heterotrimeric G protein subunit that inhibits the production of cAMP from ATP. -
Synonyms
Goα-Subunit; Gnao1; guanine nucleotide binding protein, alpha O; Gnao; alphaO; Galphao; AW050213; Guanine nucleotide binding protein G(o) subunit alpha; Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; DKFZp686O0962; G-ALPHA-o; G alpha o; G protein alpha 0; GNAO 1; Go alpha; Guanine nucleotide binding protein (G pro-tein) alpha activating activity polypeptide O; Guanine nucleotide binding protein alpha activating polypeptide; OT-THUMP00000164318; OTTHUMP00000164319;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- GNAO1 Related Articles
GNAO1 involved in several pathways and played different roles in them. We selected most pathways GNAO1 participated on our site, such as Rap signaling pathway, Circadian entrainment, Retrograde endocannabinoid signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNAO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | MAGI2;RAC3;INS1;CDC42;SKAP1;PRKCZ;LPAR3;RHOA;MAPK3 |
| Circadian entrainment | PER3;GNG10;GNAO1;PLCB1;ITPR3;GNB2;GNAS;PRKCB;PRKACB |
| Retrograde endocannabinoid signaling | MAPK1;GNG11;PLCB1;PRKACB;GNGT2;GABRR3;GNG2;PLCB4;PRKCG |
| Glutamatergic synapse | GNG8;ITPR3;GNB3;SLC1A7;TRPC1;HOMER2;PRKCA;HOMER3;GRIN2C |
| Cholinergic synapse | CHRM4;ITPR1;CHRNA4;CAMK2A;GNG4;CHRM2;AKT2;KCNJ4;AKT1 |
| Serotonergic synapse | PLA2G4F;PLA2G4C;APP;PRKCA;GNG13;GNAS;MAPK1;HTR6;HTR1B |
| GABAergic synapse | GNAO1;GABRA5;GABBR1;GABRA4;GABRB1;GABRR1;GNG7;GABARAPL1;GNG4 |
| Dopaminergic synapse | GNG11;PPP2R5A;ATF4;PPP2R3A;GNG10;KCNJ9;DRD5;PRKACA;MAOB |
| Long-term depression | ITPR1;HRAS;PRKCB;MAP2K1;PPP2R1A;PLCB1;GNAI2;GUCY1A3;GRIA2 |
| Estrogen signaling pathway | SHC3;NOS3;PRKCD;MMP2;CALM1;ATF6B;KCNJ5;HSPA6;HSP90AB1 |
| Melanogenesis | CALM3;GSK3B;FZD3;WNT3A;WNT5A;CALM2;PRKCB;PRKACBB;MC1R |
| Oxytocin signaling pathway | KCNJ14;PRKCA;CCND1;RYR1;PPP1R12A;GNAQ;MYLK2;CACNB2;RYR3 |
| Alcoholism | GM6026;CREB3;CALM4;HIST1H2AC;HDAC1;MAPK3;CALM2;GRIN2D;HIST2H3C |
| Chagas disease (American trypanosomiasis) | TGFBR1;PPP2R2B;GNA14;SMAD3;NFKB1;CALR;ACE;CCL3L1;IFNB1 |
| Toxoplasmosis | HSPA1B;CASP9;HSPA1L;IRGM;PIK3R1;MAPK3;IL10RB;LAMC2;MAP3K7 |
GNAO1 has several biochemical functions, for example, G-protein beta/gamma-subunit complex binding, G-protein coupled serotonin receptor binding, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNAO1 itself. We selected most functions GNAO1 had, and list some proteins which have the same functions with GNAO1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein beta/gamma-subunit complex binding | GNAI2;GNA11A;ADORA1;GNA11;GNA13A;GNA13B;Adcy4;GNAIA;CETN1 |
| G-protein coupled serotonin receptor binding | GNAI3;GNAZ;GNAIA;GNAI1;GNAO1;GNAO1A;GNAO1B |
| GTP binding | GEM;MFN1B;GNAT3;ARF6;GNAIA;EEF1A1L1;LSG1;HBS1L;SUCLG2 |
| GTPase activating protein binding | RGS14;CDH1;MEX3B;GNAI1;PLCD1;GAPVD1;FMNL1;TUBB;PIN1 |
| GTPase activity | RAB1BA;TUBA3D;TUBE1;RRAGD;GNG5;EEF2A.1;EIF2S3Y;RRAD;RAB39BB |
| corticotropin-releasing hormone receptor 1 binding | GNAO1;UCN;GNAO1A;CRH;GNAO1B;GNAS |
| metal ion binding | ZNF705A;CYP2Y3;CRACR2B;NR6A1B;PLEKHM1P;TRIM35-21;PPP1CC;YDJC;ZFP787 |
| mu-type opioid receptor binding | GNAO1B;GNAS;GPR177;FLNA;WLS;GNAO1A;GNAO1 |
| signal transducer activity | PPP1R12A;TAS2R109;AVPR2L;GNGT2A;OLFR8;TFG;GPR113;PLK2;FKBP1A |
GNAO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNAO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNAO1.
gtp; APP; CXCR5; Haus4; DCTN2; 15-deoxy-delta(12,14; HTT
- Q&As
- Reviews
Ask a Question for All GNAO1 Products
Required fields are marked with *
My Review for All GNAO1 Products
Required fields are marked with *
