Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

GP5

  • Official Full Name

    glycoprotein V (platelet)

  • Overview

    Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
  • Synonyms

    GP5; glycoprotein V (platelet); GPV; CD42d; platelet glycoprotein V; glycoprotein 5;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Porcine reproductive and respiratory syndrome virus (isolate Pig/United States/SD 01-08/2001) (PRRSV)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GP5-336H Recombinant Human GP5 Mammalian Cell His
Human GP5-6779H Recombinant Human GP5 protein, His & T7-tagged E.coli His/T7 Gln17~Pro242 (Accession # P40197)
Human GP5-1366H Recombinant Human GP5 Protein (Gln17-Pro242), N-His tagged E.coli N-His Gln17-Pro242
Human GP5-3296H Recombinant Human GP5 protein, His-tagged E.coli His 26-232 aa
Human GP5-3052H Recombinant Human GP5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GP5-001H Recombinant Human GP5 Protein, His-tagged Mammalian cells His
Human GP5-4207H Recombinant Human GP5 Protein (Met1-Gly523), C-His tagged Mammalian cells C-His Met1-Gly523
Human GP5-3052H-B Recombinant Human GP5 Protein Pre-coupled Magnetic Beads HEK293
Mouse Gp5-5621M Active Recombinant Mouse Glycoprotein 5 (platelet), His-tagged Mammalian cells His
Mouse Gp5-598M Active Recombinant Mouse Gp5 Protein, His-tagged Mammalian cells His Met1-Gly522
Mouse Gp5-6780M Recombinant Mouse Gp5 protein, His & T7-tagged E.coli His/T7 Ser246~Glu485 (Accession # O08742)
Mouse Gp5-3807M Recombinant Mouse Gp5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gp5-3807M-B Recombinant Mouse Gp5 Protein Pre-coupled Magnetic Beads HEK293
Rat GP5-2626R Recombinant Rat GP5 Protein Mammalian Cell His
Rat GP5-2281R-B Recombinant Rat GP5 Protein Pre-coupled Magnetic Beads HEK293
Rat GP5-2281R Recombinant Rat GP5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL20303HF Recombinant Full Length Human Platelet Glycoprotein V(Gp5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (17-560)
Mus musculus (Mouse) RFL31203MF Recombinant Full Length Mouse Platelet Glycoprotein V(Gp5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (17-567)
Porcine reproductive and respiratory syndrome virus (isolate Pig/United States/SD 01-08/2001) (PRRSV) RFL7213PF Recombinant Full Length Porcine Reproductive And Respiratory Syndrome Virus Glycoprotein 5(Gp5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-201)
Rattus norvegicus (Rat) RFL10279RF Recombinant Full Length Rat Platelet Glycoprotein V(Gp5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (17-567)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GP5 Related Articles
  • GP5 Related Research Area

GP5 involved in several pathways and played different roles in them. We selected most pathways GP5 participated on our site, such as ECM-receptor interaction, Platelet activation, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with GP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ECM-receptor interactionITGA7;GP5;VTNB;COL1A1;ITGA9;TNXB;VTN;SDC1;COL5A2A
Platelet activationPLA2G4D;RHOA;F2RL3;GP1BA;TBXA2R;APBB1IP;MAPK12;PRKCI;MYLK
Hematopoietic cell lineageIL1R1;EPOR;IL3RA;CD59;IL1B;FCER2;EPO;CD1d1;FCGR1A

GP5 has several biochemical functions, for example, collagen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GP5 itself. We selected most functions GP5 had, and list some proteins which have the same functions with GP5. You can find most of the proteins on our site.

Function Related Protein
collagen bindingLACRT;PCOLCE;PDGFB;DDR2;PCOLCE2;VWF;LUM;MTAP1A;COMP
protein bindingDNAJC7;CCNB2;FAM32A;RHNO1;NUP62L;FKBP3;MLLT4;Car8;CRP

GP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GP5.

GP9

Yu, Y; Wang, G; et al. Single-chain anti-idiotypic antibody retains its specificity to porcine reproductive and respiratory syndrome virus GP5. IMMUNOLOGY LETTERS 163:8-13(2015).
Bao, LD; Si, Q; et al. Detection of human papillomavirus and expression of osteopontin in cervical cancer specimens. MOLECULAR MEDICINE REPORTS 11:447-453(2015).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All GP5 Products

Required fields are marked with *

My Review for All GP5 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends