hip1r
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  • Official Full Name
  • huntingtin interacting protein 1 related
  • Background
  • Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
  • Synonyms
  • HIP1R; huntingtin interacting protein 1 related; HIP3; HIP12; ILWEQ; huntingtin-interacting protein 1-related protein; HIP-12; HIP1-related protein; huntingtin interacting protein 12; huntingtin-interacting protein 12;
Cat.#:HIP1R-13784HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIP1R, GST-tagged
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Cat.#:HIP1R-29320THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIP1R, His-tagged
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Cat.#:HIP1R-29HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human HIP1R, GST-tagged
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Cat.#:HIP1R-30HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human HIP1R, MYC/DDK-tagged
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Cat.#:HIP1R-7857HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human HIP1R protein, His & T7-tagged
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Cat.#:HIP1R-7635MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HIP1R Protein
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Cat.#:HIP1R-2363CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HIP1R
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Cat.#:HIP1R-789HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HIP1R cell lysate
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Involved Pathway

HIP1R involved in several pathways and played different roles in them. We selected most pathways HIP1R participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with HIP1R were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Clathrin derived vesicle budding
TGOLN2; PPIAL4A; CLVS2; CTSZ; AP1G1; AP1S1; NAPAB; HIP1RB; AP1S3A; AP3S1
Golgi Associated Vesicle Biogenesis
SNX9A; PICALMB; PPIAL4A; PICALM; SNAPIN; AP1G1; HIP1R; BLOC1S3; FTH1B; DTNBP1
Membrane Trafficking
TFR1B; NAPAA; TGOLN2; AP4B1; GOLGA2; LMAN2; GAK; NSFA; TERFA; TPD52
Vesicle-mediated transport
ANKRD28; TRAPPC3; NFX1; BLOC1S4; CLVS1; CLVS2; STXBP3; CX30.3; FTH1B; COPZ1
trans-Golgi Network Vesicle Budding
BLOC1S4; TCEAL4; DTNBP1B; SNX9A; PICALM; DNASE2; TGOLN2; AP3S1; CNO; PICALMB

Protein Function

HIP1R has several biochemical functions, for example, actin binding, clathrin binding, phosphatidylinositol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HIP1R itself. We selected most functions HIP1R had, and list some proteins which have the same functions with HIP1R. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein INO80; VPS18; TPM4; SMYHC3; DAAM1; JMY; SCINLB; KLHL20; EZRB; DNASE1
Function clathrin binding
Related Protein SYT5A; NCALD; SYT15; TOM1L1; SYT10; SNAP91; RPH3AL; SYTL1; PICALM; DOC2D
Function phosphatidylinositol binding
Related Protein PLD1; SNX32; NISCH; ARHGAP32; SH3PXD2AA; SNX18A; SH3YL1; PLD1A; PXK; SNX9B
Function protein binding
Related Protein DOK6; NKX2-5; MRPS9; ZNF830; BID; ZFHX3; FOXP1; MAGEA1; ARL3; FASTK

Interacting Protein

HIP1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HIP1R here. Most of them are supplied by our site. Hope this information will be useful for your research of HIP1R.
q53hg7_human; UBA1; UBE2N; UBE2V1; Map3k1; pi3p; Sec24c; GAK; CLTB; VCAM1; MYH9; CAPZA2; CD81; Actb