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Ifna4

  • Official Full Name

    interferon, alpha 4

  • Overview

    Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily, and are produced by a wide variety of cells types in response to challenges by foreign agents such as viruses, parasites and tumor cells.
  • Synonyms

    IFNA4; interferon, alpha 4; interferon alpha-4; IFN alpha4a; MGC142200; Interferon alpha 4 precursor; Interferon alpha 4B; Interferon alpha 76; Interferon alpha M1; IFN-alpha-4; interferon alpha-4B; interferon alpha-76; interferon alpha-M1; INFA4; IFN-alpha4a;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Yeast
  • Fc
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • SUMO
  • mFc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IFNA4-597H Active Recombinant Human IFNA4 E.coli N/A
Human IFNA4-75H Recombinant Human Interferon, Alpha 4 E.coli N/A
Human IFNA4-29H Active Recombinant Human IFNA4 protein, hFc-tagged HEK293 hFc Cys23-Asp189
Human IFNA4-175H Recombinant Human IFNA4, His tagged Insect Cell His
Human IFNA4-193H Recombinant Human IFNA4 Protein, His-tagged HEK293 His
Human IFNA4-156H Recombinant Human IFNA4 Protein, His-tagged E.coli His Ala10~Ala163
Human IFNA4-495HCL Recombinant Human IFNA4 cell lysate Insect Cell N/A
Human IFNA4-2933HCL Recombinant Human IFNA4 cell lysate Human Cell N/A
Human IFNA4-077H Active Recombinant Human IFNA4 Protein E. coli
Human IFNA4-1190H Recombinant Human IFNA4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human IFNA4-432H Active Recombinant Human IFNA4 Protein, His-tagged Yeast His Cys24-Asp189
Human IFNA4-6663H Recombinant Human IFNA4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IFNA4-3070H Recombinant Human IFNA4 protein, His-SUMO-tagged E.coli His-SUMO 24-189aa
Human IFNA4-3597H Recombinant Human IFNA4 Protein (Ala10-Ala163), His tagged E.coli His Ala10-Ala163
Mouse Ifng4-122M Active Recombinant Mouse Ifng4 protein, Fc-tagged HEK293 Fc Cys 25-Glu 186
Mouse Ifna4-596M Active Recombinant Mouse Ifna4 Mammalian Cell N/A
Mouse Ifna4-122M Active Recombinant Mouse Ifna4, Fc-tagged Human Cell Fc
Mouse Ifna4-157M Recombinant Mouse Ifna4 Protein, His-tagged E.coli His Asp26~Glu186
Mouse IFNA4-183M Recombinant Mouse Ifna4, His tagged Human Cell GST
Mouse IFNA4-846MCL Recombinant Mouse IFNA4 cell lysate Human Cell N/A
Mouse IFNa4-3275M Active Recombinant Mouse IFNa4 protein, His-tagged HEK293 His Met1-Glu186
Mouse Ifna4-10565M Recombinant Mouse Ifna4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ifna4-10565M-B Recombinant Mouse Ifna4 Protein Pre-coupled Magnetic Beads HEK293
Rat Ifna4-7447R Active Recombinant Rat Ifna4 protein, hFc-tagged HEK293 hFc Cys24-Lys189
Rat Ifna4-158R Recombinant Rat Ifna4 Protein, His-tagged E.coli His Arg33~Lys189
Rat IFNA4-1412RCL Recombinant Rat IFNA4 cell lysate Human Cell N/A
Cynomolgus IFNA4-8840C Active Recombinant Cynomolgus IFNA4 protein, mFc-tagged HEK293 mFc Met1-Asn189
Cynomolgus Monkey IFNA4-989CCL Recombinant Cynomolgus IFNA4 cell lysate Human Cell N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Ifna4 Related Articles
  • Ifna4 Related Gene Family
  • Ifna4 Related Research Area

Ifna4 involved in several pathways and played different roles in them. We selected most pathways Ifna4 participated on our site, such as Cytokine-cytokine receptor interaction, Regulation of autophagy, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ifna4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL12BA;TNFRSF11B;PF4V1;TNFSF18;CCR9A;PPBP;PDGFRB;CXCR4;EPOR
Regulation of autophagyIFNA16;ATG4D;ATG12;IFNA13;IFNA6;PIK3C3;ATG7;PRKAA2;INS2
PIK-Akt signaling pathwayFGF17;SPP1;IKBKB;GYS2;PIK3CA;G6PC;HSP90AA1;ITGA7;LAMA1
Toll-like receptor signaling pathwayMAPK14B;MAPK13;IFNB1;CXCL9;NFKBIA;RIPK1L;IFNA7;IFNA16;SPP1
RIG-I-like receptor signaling pathwayISG15;MAPK14B;CASP8;IFNA2;TRAF2;IFNA4;TANK;IFNB1;Ifna11
Cytosolic DNA-sensing pathwayIFNA1;POLR3G;IFNA17;IFNA21;IFNA10;OSTN;POLR3K;NFKBIAA;POLR3GLB
Jak-STAT signaling pathwayIFNA12;IL27RA;STAT4;HRASA;Il23a;AKT1;FHL1A;Ifnl2;AOX1
Natural killer cell mediated cytotoxicityPRKCA;VAV1;Ifna11;Fasl;KIR2DS5;PTK2B;ITGAL;IFNA14;PIK3R5
TuberculosisMAPK13;STAT1;CYCS;MAPK11;CAMK2G;ATP6V0A1;BCL2;HLA-DQA2;RFXANK
Hepatitis CRAF1;PPP2CB;CLDN9;PPP2R2B;CXCL8;PPARA;TRAF6;OAS2;IFNA16
Hepatitis BPRKCG;BCL2;ATF4;MAVS;MAPK1;Ifna11;TLR4;STAT3;RB1
MeaslesPIK3CA;Il2;TP53;IRF7;IFNA12;IFNG;CCNE2;cgr2b;IFNA13
Influenza AEP300;CYCS;GSK3B;PRKCA;CASP1;BCL2L2-PABPN1;IFIH1;MAPK9;TNF
Herpes simplex infectionIFNA16;Ccl12;IKBKG;ABCB3L1;IFNA5;HLA-F;CDC34A;PPP1CB;BLB2
AutoiIFNA21;IFNA1;HLA-DRB4;FASLG;H2-Q10;HLA-DOA;IFNA8;IL5;HLA-DRB3
ne thyroid diseaseHLA-DRB1;FASLG;HLA-DRB3;CD28;IFNA17;HLA-DRB5;TSHB;HLA-F;CD40

Ifna4 has several biochemical functions, for example, cytokine activity, protein binding, type I interferon receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ifna4 itself. We selected most functions Ifna4 had, and list some proteins which have the same functions with Ifna4. You can find most of the proteins on our site.

Function Related Protein
cytokine activityGm13290;IFNPHI1;BMP4;IL1A;Il1f9;CMTM4;WNT2;LFT2;CMTM6
protein bindingMYD88;TUBA1B;SOX7;RNF6;USP15;ZFP259;C6orf226;TUBA1C;UQCRB
type I interferon receptor bindingIFNA17;IFNA8;IFNA21;IFNA13;IFNPHI3;IFNB;GM13279;GM13285;IFNA2

Ifna4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ifna4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ifna4.

ALDOA

Park, JH; Joo, CK; et al. Comparative Study of Tacrolimus and Bevacizumab on Corneal Neovascularization in Rabbits. CORNEA 34:449-455(2015).
Aydinoglu-Candan, O; Araz-Ersan, B; et al. Anti-interferon alpha antibodies and autoantibodies in patients with Beh double dagger et's disease uveitis treated with recombinant human interferon alpha-2a. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY 253:457-465(2015).
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