NDUFA10
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
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Overview
The protein encoded by this gene belongs to the complex I 42kDA subunit family. Mammalian complex I is the first enzyme complex in the electron transport chain of mitochondria. It is composed of 45 different subunits. This protein is a component of the hydrophobic protein fraction and has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. -
Synonyms
NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10 (42kD); NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; CI 42k; complex I 42kDa subunit; CI 42KD; CI-42k; Complex I-42kD; MGC5103; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10 42kDa; NADH ubiquinone oxidoreductase 42 kDa subunit mitochondrial precursor; NADH-ubiquinone oxidoreductase 42 kDa subunit; ndufa10l; CI-42KD;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- N/A
- T7
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NDUFA10-832H | Recombinant Human NDUFA10, T7-tagged | E.coli | T7 |
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| Human | NDUFA10-28707TH | Recombinant Human NDUFA10, His-tagged | E.coli | His |
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| Human | NDUFA10-3925HCL | Recombinant Human NDUFA10 293 Cell Lysate | HEK293 | N/A |
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| Mouse | NDUFA10-10511M | Recombinant Mouse NDUFA10 Protein | Mammalian Cell | His |
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| Mouse | NDUFA10-5963M | Recombinant Mouse NDUFA10 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | NDUFA10-5963M-B | Recombinant Mouse NDUFA10 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | NDUFA10-3933R | Recombinant Rat NDUFA10 Protein | Mammalian Cell | His |
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| Rat | NDUFA10-3591R | Recombinant Rat NDUFA10 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | NDUFA10-3591R-B | Recombinant Rat NDUFA10 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | NDUFA10-9981Z | Recombinant Zebrafish NDUFA10 | Mammalian Cell | His |
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| Chicken | NDUFA10-2906C | Recombinant Chicken NDUFA10 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
NDUFA10 involved in several pathways and played different roles in them. We selected most pathways NDUFA10 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFA10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Oxidative phosphorylation | ATP6V1BA;NDUFA9;COX15;ATP6V1E1B;NDUFB3;ATP6V0A2B;NDUFB7;NDUFS1;ATP5D |
| Metabolic pathways | NT5C1A;ASMT;ALPI;HSD17B12B;CYP2J6;AMD1;MGAT2;LIPC;COMTB |
| Non-alcoholic fatty liver disease (NAFLD) | NDUFS3;NDUFB9;NDUFC2;NDUFB2;RELA;PRKAB2;NFKB1;MAPK9;MAP3K11 |
| Alzheimers disease | ATP5J;NDUFA3;COX4I2;mt-Atp8;CASP8;COX5A;NDUFS8;APP;NDUFS3 |
| Parkinsons disease | UQCRB;GNAL;NDUFS5;SEPT5;UBA7;GNAI2;ATP5C1;SDHA;APAF1 |
| Huntingtons disease | NRF1;NDUFA4;PLCB1;ATP5F1;COX6B1;TBPL1;IFT57;TAF4B;NDUFB7 |
NDUFA10 has several biochemical functions, for example, NADH dehydrogenase (ubiquinone) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFA10 itself. We selected most functions NDUFA10 had, and list some proteins which have the same functions with NDUFA10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NADH dehydrogenase (ubiquinone) activity | NDUFS7;NDUFS5;NDUFS2;NDUFS8;NDUFB3;NDUFA10;NDUFC1;NDUFV2;NDUFB8 |
NDUFA10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFA10 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFA10.
NDUFA2; BRCC3; MME; Rab5c; PLK1; NDUFA6; NDUFA9; Rmdn3; ELMSAN1; NDUFA11; HDAC11; VAPA; GOLT1B; WIPI2
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, NDUFA10 mutations can be inherited, and genetic counseling is important for families affected by these mutations.
By elucidating the role of NDUFA10 in mitochondrial function, research can identify potential drug targets and pathways for therapeutic intervention.
Immunohistochemistry and western blotting techniques can be used to assess NDUFA10 protein expression in patient samples.
Yes, animal models such as mouse models with NDUFA10 mutations are used to study the pathology and potential treatments for these diseases.
The specific type and location of NDUFA10 mutations can influence the severity and clinical manifestations of mitochondrial diseases.
Customer Reviews (3)
Write a reviewWhat truly distinguishes the NDUFA10 Protein is the unparalleled technical support provided by the manufacturer.
I highly recommend the NDUFA10 Protein to fellow researchers seeking a high-quality protein that not only meets their experimental requirements but is also accompanied by exceptional technical support.
The NDUFA10 Protein's consistent stability and robust performance make it an indispensable tool for studying its multifaceted roles and mechanisms within vital biochemical pathways and cellular processes.
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