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POMGNT1

Official Full Name

protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase
Overview

The protein encoded by this gene is a type II transmembrane protein that resides in the golgi. It participates in O-mannosyl glycosylation, and is specific for alpha linked terminal mannose. Mutations in this gene are associated with muscle-eye-brain (MEB) disease. Alternatively spliced transcript variants have been found for this gene.
Synonyms

POMGNT1; protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase; protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; FLJ20277; MGAT1.2; protein O mannose beta 1; 2 N acetylglucosaminyltransferase; UDP-GlcNAc:alpha-D-mannoside be;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell
Mammalian cells
Sf21 Insect Cell

Tag

C
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	POMGNT1-289H	Active Recombinant Human POMGNT1, His-tagged	Sf21 Insect Cell	His		Inquiry
Human	POMGNT1-27934TH	Recombinant Human POMGNT1, His-tagged	E.coli	His		Inquiry
Human	POMGNT1-237H	Recombinant Human POMGNT1 Protein, His-tagged	HEK293	His		Inquiry
Human	POMGNT1-4975H	Recombinant Human POMGNT1 Protein (Leu59-Thr660), C-His tagged	Mammalian cells	C-His	Leu59-Thr660	Inquiry
Mouse	POMGNT1-13118M	Recombinant Mouse POMGNT1 Protein	Mammalian Cell	His		Inquiry
Mouse	POMGNT1-6937M	Recombinant Mouse POMGNT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	POMGNT1-6937M-B	Recombinant Mouse POMGNT1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	POMGNT1-4575R	Recombinant Rat POMGNT1 Protein	Mammalian Cell	His		Inquiry
Rat	POMGNT1-4235R	Recombinant Rat POMGNT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	POMGNT1-4235R-B	Recombinant Rat POMGNT1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	POMGNT1-3818Z	Recombinant Zebrafish POMGNT1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

POMGNT1 involved in several pathways and played different roles in them. We selected most pathways POMGNT1 participated on our site, such as Other types of O-glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with POMGNT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Other types of O-glycan biosynthesis	C3orf64;ST3GAL3B;FUT9A;GXYLT1B;GLT25D2;MGAT5B;LFNG;B3GAT2;ST3GAL3

POMGNT1 has several biochemical functions, for example, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POMGNT1 itself. We selected most functions POMGNT1 had, and list some proteins which have the same functions with POMGNT1. You can find most of the proteins on our site.

Function	Related Protein
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	B3GNT6;POMGNT1;B3GNT3
protein binding	RHOT2;MAD1L1;DNAJB5;TUBG1;BLOC1S4;MLL1;U2AF1;HACL1;RELB

POMGNT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POMGNT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POMGNT1.

LNX1; CXCL8; SOX6; BRCA1; ZBTB18; SLC38A1