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TAF5L

  • Official Full Name

    TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa

  • Overview

    The product of this gene belongs to the WD-repeat TAF5 family of proteins. This gene encodes a protein that is a component of the PCAF histone acetylase complex. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors to facilitate complex assembly and transcription initiation. The encoded protein is structurally similar to one of the histone-like TAFs, TAF5. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
  • Synonyms

    TAF5L; TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF5 like RNA polymerase II, p300/CBP associated factor (PCAF) associated factor, 65 kD; TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L; PAF65B; PCAF associated factor 65 beta; 1110005N04Rik; AI849020; OTTHUMP00000037470; OTTHUMP00000037471; PAF65 beta; PAF65-beta; PCAF-associated factor 65 beta; TAF 5L; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kD; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor 65 kDa; TAF5 like RNA polymerase II p300/CBP associated factor (PCAF) associated factor; TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65 kDa subunit 5L; TAF5 like RNA polymerase II p300/CBP associated factor associated factor 65kDa; Taf5l protein; TAF5L_HUMAN;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TAF5L-30936TH Recombinant Human TAF5L, His-tagged E.coli His
Human TAF5L-3105H Recombinant Human TAF5L, His-tagged E.coli His 1-325aa
Human TAF5L-1268HCL Recombinant Human TAF5L 293 Cell Lysate HEK293 N/A
Human TAF5L-3549H Recombinant Human TAF5L protein, GST-tagged E.coli GST 1-325aa
Mouse TAF5L-16398M Recombinant Mouse TAF5L Protein Mammalian Cell His
Mouse TAF5L-8969M Recombinant Mouse TAF5L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TAF5L-8969M-B Recombinant Mouse TAF5L Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TAF5L-4609R Recombinant Rhesus monkey TAF5L Protein, His-tagged Mammalian Cell His
Rhesus Macaque TAF5L-4425R-B Recombinant Rhesus Macaque TAF5L Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TAF5L-4425R Recombinant Rhesus Macaque TAF5L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TAF5L-10225Z Recombinant Zebrafish TAF5L Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TAF5L involved in several pathways and played different roles in them. We selected most pathways TAF5L participated on our site, such as Basal transcription factors, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF5L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Basal transcription factorsERCC2;GTF2H1;TAF11;GTF2I;GTF2F1;TAF5;TAF3;GTF2A1;TAF6
Herpes simplex infectionSRSF9;CD74;DDX58;C3A.2;CRFB2;IFNG1-2;MHC2A;SRSF2A;TNFRSF1A

TAF5L has several biochemical functions, for example, contributes_to histone acetyltransferase activity, transcription coactivator activity, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF5L itself. We selected most functions TAF5L had, and list some proteins which have the same functions with TAF5L. You can find most of the proteins on our site.

Function Related Protein
contributes_to histone acetyltransferase activityTADA1;TADA3;ELP4;ING3;TAF10;TAF6L;KAT2A;TEX30;TAF5L
transcription coactivator activityHAND1;ELF3;TADA1;BRCA1;COPS5;YAF2;SP100;CITED1;SMARCA2
transcription factor activity, sequence-specific DNA bindingPOU1F1;GATA2A;RUNX1T1;ZNF483;CBFA2T3;NR1D4B;FOXI1;GATA1A;FOXG1A

TAF5L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF5L here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF5L.

KAT2B; USP22; TTR; H2AFX; ANXA7; CDKN1A; TSC22D1; KAT2A; CCDC101; CDC5L

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