ARHGAP12B
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Zebrafish | ARHGAP12B-11122Z | Recombinant Zebrafish ARHGAP12B | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
ARHGAP12B involved in several pathways and played different roles in them. We selected most pathways ARHGAP12B participated on our site, such as Rho GTPase cycle, Signal Transduction, Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGAP12B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Rho GTPase cycle | ARHGAP10;ARHGAP26;ARHGAP23;ARHGEF18;AKAP13;RHOT2;TAGAP1;ARHGAP12B;RHOU |
Signal Transduction | RNF41;NF2A;OPN4.1;LGR6;MYO7A;RHOF;RAMP2;IFT88;PTHLHA |
Signaling by Rho GTPases | ARHGAP11A;ARHGAP12;ARHGAP20;ARHGAP25;ARHGAP31;RHOV;ARHGAP17;DLC1;ARHGAP6 |
ARHGAP12B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGAP12B itself. We selected most functions ARHGAP12B had, and list some proteins which have the same functions with ARHGAP12B. You can find most of the proteins on our site.
Function | Related Protein |
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ARHGAP12B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGAP12B here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGAP12B.
- Q&As
- Reviews
Q&As (16)
Ask a questionThe regulatory mechanisms controlling ARHGAP12B expression have not been extensively studied. However, transcription factors or signaling pathways may potentially regulate its expression. Further research is needed to identify its regulators.
ARHGAP12B exhibits a moderate level of conservation across different species, including mammals. However, the extent of conservation and its functional implications need further investigation.
No specific genetic variants or mutations in ARHGAP12B have been identified as causative factors for neurodevelopmental disorders thus far. However, given its potential role in brain development and its association with human-specific features, further genetic studies may reveal potential links between ARHGAP12B and neurodevelopmental disorders.
Although not yet fully characterized, it is plausible that ARHGAP12B can interact with Rho family GTPases, given its predicted RhoGAP domain. These interactions could potentially regulate the activity and signaling of these GTPases.
Currently, there are no well-characterized genetic polymorphisms reported in the ARHGAP12B gene. However, further research is necessary to identify common polymorphisms and their potential functional implications.
Considering its predicted role in Rho GTPase signaling, which is critical for cell migration and invasion, it is possible that ARHGAP12B could influence these cellular processes. However, functional studies are needed to determine the direct impact of ARHGAP12B on cell migration and invasion.
There is currently no known association between ARHGAP12B and neurodevelopmental disorders. However, genetic studies and functional investigations are required to explore its potential contributions to these conditions.
The involvement of ARHGAP12B in developmental processes is not well established. However, as it is expressed in the brain, it may play a role in neuronal development or synaptic plasticity.
The specific cellular or physiological roles of ARHGAP12B are still largely unknown. However, given its potential involvement in cytoskeletal regulation, it may play a role in cell migration, adhesion, or other processes requiring dynamic cytoskeletal rearrangements.
There are currently no known disease associations or mutations identified in the ARHGAP12B gene. However, further research is needed to fully characterize its genetic variants and assess any potential disease links.
ARHGAP12B contains a predicted RhoGAP domain, which suggests its potential to interact with Rho family GTPases. However, other protein-protein interaction domains have not been reported.
The post-translational modifications of ARHGAP12B have not been extensively studied. However, it is predicted to contain several phosphorylation sites, suggesting potential regulation through phosphorylation-mediated events.
ARHGAP12B shows a tissue-specific expression pattern, with higher levels reported in the brain, particularly in the cortex and hippocampus. It is also expressed in the testis, kidney, and adrenal gland, albeit at lower levels.
Currently, there are no known specific inhibitors or activators that directly modulate ARHGAP12B activity. Further research is warranted to identify potential molecules capable of modulating its function.
The protein interactions and potential complex formations involving ARHGAP12B are not well characterized. Further studies are needed to identify its binding partners and elucidate its role in signaling pathways.
Given the limited knowledge of ARHGAP12B's function and its role in disease, it is currently unclear if it can be targeted for therapeutic interventions. More research is needed to determine its potential as a therapeutic target.
Customer Reviews (8)
Write a reviewThe manufacturer can further support researchers by providing customized solutions tailored to their specific needs.
This collaborative partnership greatly contributes to the success of my research projects and facilitates meaningful contributions to the scientific community.
Its reliability, versatility, and ability to deliver clear and reliable results make it a top choice for researchers in need of a high-quality protein for their experiments.
This enhanced visibility and distinctness of the protein bands greatly aided in the accurate analysis and interpretation of my Western Blotting results.
The manufacturer's support and expertise further enhance the utility of ARHGAP12B in my experimental work, ensuring reliable and high-quality results.
Another advantage of using ARHGAP12B protein in trials is its potential as a therapeutic agent.
ARHGAP12B protein has exhibited remarkable performance in Western Blotting experiments.
The reliable and high-quality results obtained using ARHGAP12B protein make it an excellent choice for researchers studying protein structures.
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