ARPC5LA
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | ARPC5LA-10856Z | Recombinant Zebrafish ARPC5LA | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
ARPC5LA involved in several pathways and played different roles in them. We selected most pathways ARPC5LA participated on our site, such as Endocytosis, Regulation of actin cytoskeleton, Salmonella infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARPC5LA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | CHMP2BA;SNX2;ERBB3B;ADRB1;MDM2;MHC1UXA2;ARPC5LA;ARFGAP2;SPG21 |
| Regulation of actin cytoskeleton | MSN;ITGB6;CHRM2A;PAK6B;PIP5K1BB;ARAF;FGD3;MYLPFB;ARPC5B |
| Salmonella infection | IL18;CD14;ARPC4L;CCL4;RHOG;KLC4;RAB7;MAPK11;ROCK2B |
ARPC5LA has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ARPC5LA itself. We selected most functions ARPC5LA had, and list some proteins which have the same functions with ARPC5LA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
ARPC5LA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARPC5LA here. Most of them are supplied by our site. Hope this information will be useful for your research of ARPC5LA.
- Q&As
- Reviews
Q&As (5)
Ask a questionCurrently, there are no specific diseases or disorders directly linked to ARPC5LA dysfunction. However, as a component of the Arp2/3 complex, dysregulation or mutations in other subunits of the complex have been associated with various cellular abnormalities, including developmental disorders, cancer metastasis, and autoimmune diseases.
ARPC5LA is primarily localized in the cytoplasm of cells, where it interacts with other subunits of the Arp2/3 complex. However, it may also transiently localize to the plasma membrane or other cellular compartments during dynamic processes such as cell migration or membrane remodeling.
As a subunit of the Arp2/3 complex, ARPC5LA interacts with other subunits of the complex, including ARPC1, ARPC2, ARPC3, and ARPC4. It also interacts with Nucleation Promoting Factors (NPFs), which are proteins that initiate actin filament nucleation and regulate Arp2/3 complex activity.
ARPC5LA is expressed in a wide range of cell types and tissues, suggesting that it has a general role in actin cytoskeleton regulation. However, the relative abundance or specific functions of ARPC5LA in different tissues or cell types may vary.
Since ARPC5LA is an integral part of the Arp2/3 complex, its activity can potentially be targeted by drugs or inhibitors that modulate the function of the entire complex. Small-molecule inhibitors that interfere with Arp2/3 complex activity or inhibitors that disrupt the interaction between the complex and NPFs may indirectly affect the function of ARPC5LA.
Customer Reviews (3)
Write a reviewIn addition to the remarkable protein quality, the manufacturer provides excellent technical support, proving to be a valuable resource when troubleshooting experimental challenges.
Whether investigating metabolic pathways, studying enzymatic activity, or exploring drug targets, this protein offers versatility and reliability, allowing for accurate and meaningful data collection.
Their expertise and prompt assistance can effectively address any concerns or challenges that may arise during the experimental process.
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