ATXN1A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | ATXN1A-3958Z | Recombinant Zebrafish ATXN1A | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
ATXN1A involved in several pathways and played different roles in them. We selected most pathways ATXN1A participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ATXN1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ATXN1A has several biochemical functions, for example, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATXN1A itself. We selected most functions ATXN1A had, and list some proteins which have the same functions with ATXN1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | DHX34;ADARB1A;RBM3;CDKN2AIP;NSUN3;HDLBPA;SMARCE1;EIF4E1C;ATXN1L |
ATXN1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATXN1A here. Most of them are supplied by our site. Hope this information will be useful for your research of ATXN1A.
- Q&As
- Reviews
Q&As (6)
Ask a questionATXN1A gene is associated with spinocerebellar ataxia type 1 (SCA1). SCA1 is an inherited neurological disorder caused by mutations in the ATXN1A gene.
The expression of ATXN1A gene is affected by a variety of regulatory mechanisms, including the binding of transcriptional regulators, epigenetic modification, and regulation by non-coding RNA.
The ATXN1A mutation leads to the expansion of glutamine repeats in the ATXN1A protein, resulting in the formation of abnormal polyglutamic acid protein. The abnormal accumulation of this protein can lead to abnormal function and degenerative changes of nerve cells, triggering the occurrence of SCA1.
The protein encoded by the ATXN1A gene plays an important role in the nervous system, involving in cell cycle regulation, transcriptional regulation, and protein degradation.
This gene is expressed in several tissues, but its expression is higher in the central nervous system, especially in the cerebellum and spinal cord.
Yes, the ATXN1A gene interacts with other genes to form a complex regulatory network. For example, ATXN1A protein interacts with Capicua (CIC) protein to participate in transcriptional regulation.
Customer Reviews (3)
Write a reviewThe high activity of ATXN1A ensures its stable performance, making it a preferred choice for researchers.
The wide applicability of ATXN1Aeins makes them play a key role in many fields of research and promotes the progress of science.
This high stability of ATXN1A ensures its stable properties, making it a preferred choice for researchers.
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