Ins1
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Official Full Name
insulin 1
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Synonyms
INS1;insulin 1;insulin-1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Mouse
- Rat
- Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- Yeast
- GST
- His
- His (Fc)
- Avi
- Myc
- His|Myc
- His|SUMO
- Tag Free
- Involved Pathway
- Protein Function
- Interacting Protein
Ins1 involved in several pathways and played different roles in them. We selected most pathways Ins1 participated on our site, such as Ras signaling pathway, Rap signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ras signaling pathway | PIK3CG;RAC1;ETS2;FGF7;RASGRP3;RASGRF2;PLD2;PLA2G4A;IKBKG |
| Rap signaling pathway | LPAR4;FGF19;HGF;PRKCZ;PDGFA;PIK3R3;FGF11;APBB1IP;PDGFD |
| cGMP-PKG signaling pathway | MYLK;SLC25A31;PPP3R2;BNP;GNA12;RGS2;MYLK4;ITPR1;VDAC1 |
| HIF- signaling pathway | MKNK2;PLCG2;MKNK1;LTBR;HMOX1;CUL2;CAMK2B;IGF1R;FLT1 |
| FoxO signaling pathway | NLK1;TGFB1;PRKAG3;CDKN1BA;INSB;FOXO3;PLK2;AKT2;CDKN1BB |
| Phospholipase D signaling pathway | DGKZ;PDGFA;LPAR2;SHC3;GNA12;PLD1;MAP2K1;KRAS;GRM1 |
| Oocyte meiosis | CALM3A;YWHAZ;RPS6KA3;CAMK2G1;FBXW11;CUL1;INS1;PPP1CAA;SGOL1 |
| Regulation of autophagy | IFNA2;PRKAA1;IFNA7;IFNA8;ATG10;IFNG1-2;ATG4D;ULK3;Ifna15 |
| mTOR signaling pathway | MTOR;VEGFAA;INS1;RPS6KA3B;PIK3R5;RRAGC;RPS6KA1;RHEB;RB1CC1 |
| PIK-Akt signaling pathway | FGF13;ANGPT2;PIK3CB;FGF9;IBSP;PPP2R3C;LPAR4;CREB5;LPAR6 |
| AMPK signaling pathway | PFKP;CREB3L1;FBP1;PIK3CD;PIK3R3;AKT1S1;Scd1;AKT2;RAB2A |
| Regulation of actin cytoskeleton | LIMK1A;FGF2;ITGA6;SOS1;PPP1CB;FGFR1;ITGAL;ITGA1;ABI2 |
| Insulin signaling pathway | EIF4E1B;RAF1A;EIF4EA;PRKAB1;FLOT1;INSRB;AKT2L;PIK3R5;ARAF |
| Insulin secretion | CCKAR;SLC2A2;RAPGEF4;RAB3A;KCNMB4;ATP1A1;PCLO;KCNMB2;CAMK2G |
| Ovarian steroidogenesis | IGF1R;LDLR;PTGS2;LHCGR;ALOX5;SCARB1;HSD3B4;ACOT2;HSD3B6 |
| Progesterone-mediated oocyte maturation | HSP90AA1;PIK3CG;GNAI1;PRKACBA;CCNA1;IGF1R;MAPK9;PPP1R2P9;RAF1A |
| Prolactin signaling pathway | ESR1;AKT1;MAP2K2;PPIB;TNFRSF11A;MAPK1;NFKB1;AKT2;MAP2K1 |
| Regulation of lipolysis in adipocytes | GNAI3;IRS1;INS2;PTGS1;GNAI1;PDE3B;NPR1;NPY;PIK3CG |
| Type II diabetes mellitus | PKLR;INS1;INS;PIK3R1;PIK3CA;PIK3CG;MAPK9;SOCS4;INS2 |
| Insulin resistance | G6PC3;PIK3R1;NFKB1;SLC2A2;PRKAA2;IRS2;RPS6KA3B;GFPT2;SLC2A1A |
| Non-alcoholic fatty liver disease (NAFLD) | INS2;ADIPOR1;SDHB;COX8C;PPARA;INSR;COX7A2;MAP3K11;PKLR |
| Type I diabetes mellitus | HLA-A;HLA-F;PRF1;ICA1;IL1A;FAS;TNF;HLA-DOB;HLA-B |
| Maturity onset diabetes of the young | NEUROG3;HHEX;FOXA2;INS;PAX6;RFX6;NKX6;IAPP;NEUROD1 |
| Aldosterone-regulated sodium reabsorption | ATP1A2;ATP1B4;SFN;PIK3R1;KCNJ1;PIK3CA;INSR;ATP1A1;ATP1A4 |
| Prostate cancer | ACTL6B;SPINK1;CPN1;PIK3CA;BRAF;IKBKB;TCF7;CCNE1;CCNE2 |
Ins1 has several biochemical functions, for example, chaperone binding, hormone activity, insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins1 itself. We selected most functions Ins1 had, and list some proteins which have the same functions with Ins1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chaperone binding | HSCB;DNAJB2;ST13;TSC1;TBCD;ATP1A1;BAG3;UBL4A;BAG5 |
| hormone activity | INS1;SMTLA;AMH;INHBAB;PYY;LHB;PRL3C1;TG;PTHLH |
| insulin receptor binding | DOK5;PTPN11;IGF1;PHIP;IRS1;SNX2;INS2;INS1;DOK2 |
| protease binding | SERPINA1A;SERPINB9;BDKRB2;ITGB3;DERL1;Serpina1c;CAST;CST3;TNF |
Ins1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins1.
Gopc; Copb1
- Q&As
- Reviews
Q&As (7)
Ask a questionThe molecular weight of INS1 is approximately 5.8 kDa.
INS1 facilitates glucose uptake by muscle cells.
INS1 and INS2 are both insulin isoforms, but they differ slightly in their amino acid sequence.
The half-life of INS1 in the bloodstream is approximately 4-6 minutes.
INS1 secretion increases in response to elevated blood glucose levels.
Yes, INS1 also plays a role in protein and lipid metabolism.
INS1 binds to insulin receptors on the surface of target cells.
Customer Reviews (3)
Write a reviewConsistency in the product's behavior across experimental conditions enhanced the credibility of our findings.
The product's role in modulating intricate signaling pathways played a pivotal role in our scientific breakthroughs.
Comprehensive documentation streamlined the integration of the product into our experimental workflow.
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