MGST1
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Official Full Name
microsomal glutathione S-transferase 1
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Overview
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Four transcript variants of this gene encode one protein isoform. -
Synonyms
MGST1; microsomal glutathione S-transferase 1; GST12; MGST I; Glutathione S transferase 12; MGST 1; MGST; MGST1_HUMAN; Microsomal GST 1; Microsomal GST-1; Microsomal GST-I; glutathione S-transferase 12; MGST-I;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Chicken
- Cynomolgus Monkey
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Sus scrofa (Pig)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|GST
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | MGST1-220H | Recombinant Human MGST1 | Mammalian Cell | His | ||
Human | MGST1-30203TH | Recombinant Human MGST1 | Wheat Germ | N/A | 155 amino acids | |
Human | MGST1-1110HCL | Recombinant Human MGST1 cell lysate | N/A | |||
Human | MGST1-2439H | Recombinant Human MGST1 Protein, His-tagged | E.coli | N-His | Thr34-Pro128 | |
Human | MGST1-5309H | Recombinant Human MGST1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | MGST1-6522HF | Recombinant Full Length Human MGST1 Protein, GST-tagged | In Vitro Cell Free System | GST | 155 amino acids | |
Human | MGST1-305HF | Recombinant Full Length Human MGST1 Protein | In Vitro Cell Free System | 155 amino acids | ||
Human | MGST1-3473H | Recombinant Human MGST1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | MGST1-3473H-B | Recombinant Human MGST1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Mgst1-2653M | Recombinant Mouse Mgst1 protein, His & GST-tagged | E.coli | His/GST | Met8~Leu155 (Accession # Q91VS7) | |
Rat | Mgst1-1777R | Recombinant Rat Mgst1 Protein, His-tagged | E.coli | N-His | Gln6-Leu155 | |
Bos taurus (Bovine) | RFL7688BF | Recombinant Full Length Bovine Microsomal Glutathione S-Transferase 1(Mgst1) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-155) | |
Cynomolgus Monkey | MGST1-692C | Recombinant Cynomolgus MGST1 Protein, His-tagged | Mammalian Cell | His | ||
Cynomolgus Monkey | MGST1-438C | Recombinant Cynomolgus Monkey MGST1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Cynomolgus Monkey | MGST1-438C-B | Recombinant Cynomolgus Monkey MGST1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Homo sapiens (Human) | RFL30785HF | Recombinant Full Length Human Microsomal Glutathione S-Transferase 1(Mgst1) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-155) | |
Mus musculus (Mouse) | RFL27854MF | Recombinant Full Length Mouse Microsomal Glutathione S-Transferase 1(Mgst1) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-155) | |
Rattus norvegicus (Rat) | RFL31942RF | Recombinant Full Length Rat Microsomal Glutathione S-Transferase 1(Mgst1) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-155) | |
Sus scrofa (Pig) | RFL1101SF | Recombinant Full Length Pig Microsomal Glutathione S-Transferase 1(Mgst1) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (2-155) | |
Chicken | MGST1-3869C | Recombinant Chicken MGST1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- MGST1 Related Articles
MGST1 involved in several pathways and played different roles in them. We selected most pathways MGST1 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with MGST1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Glutathione metabolism | GPX4B;GSTM;IDH2;GSS;OPLAH;GCLC;MGST1.1;GSTAL;GSTK1 |
Metabolism of xenobiotics by cytochrome P | MGST1;UGT1A6A;UGT2A1;CBR1;ALDH3B1;GSTT1B;CBR1L;UGT1A9;ALDH1A3 |
Drug metabolism - cytochrome P | UGT1A7;UGT1A3;GSTO1;MGST2;UGT2B7;UGT1A7C;GSTM5;GSTA4;GSTT2B |
Chemical carcinogenesis | NAT1;CYP2C54;FAM84B;AHA-1;ADH4;GSTP2;Nat3;CYP1B1;ALDH3A1 |
MGST1 has several biochemical functions, for example, glutathione binding, glutathione peroxidase activity, glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MGST1 itself. We selected most functions MGST1 had, and list some proteins which have the same functions with MGST1. You can find most of the proteins on our site.
Function | Related Protein |
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glutathione binding | GSTP2;GSTM4;GSTM2;GPX1;GSS;LANCL1;PTGES2;GSTM7;PTGES |
glutathione peroxidase activity | GPX6;LTC4S;MGST1;MGST3;MGST2;GPX1;GSTZ1;GPX5;GPX3 |
glutathione transferase activity | MGST1;EEF1G;GDAP1;MGST3;GSTT2B;GSTT1;GSTA1;GSTM7;GSTM6 |
protein binding | KCTD13;IFRD2;ZCCHC10;SRSF3;COA5;RPL12;NKG7;RGS19;SOX9A |
protein homodimerization activity | CAMK2B;CADM2A;PVRL1;PRMT2;CPNE1;CARS;KCNK3;RIPK2;GYS2 |
MGST1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MGST1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MGST1.
NELFB; ERBB2
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