Active GMP Recombinant Human IL15 Protein
Cat.No. : | IL15-01HG |
Product Overview : | Recombinant human IL15 protein, was expressed in CHO-K1 cell-derived in an animal component free process under cGMP guidelines. |
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Description : | The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. |
Source : | CHO-K1 |
Species : | Human |
Form : | Lyophilized powder |
Endotoxin : | <20 EU/mg |
Bio-activity : | >2.0 x 10^6 IU/mg |
Purity : | >95.0% by high performance liquid chromatography (SEC-HPLC) and SDS-PAGE. |
Storage Buffer : | 10mM Phosphate-Buffered Saline (pH 7.2) |
Storage : | Stable storage at 4℃ for 7-10 days; for long-term storage, please store at -20℃ after dispensing. |
Sterility : | Sterility |
Instructions : | It is recommended that lyophilized GMP rhIL15 be dissolved in water for injection or sterilized ultrapure water at a concentration of not less than 100 μg/ml, pending further dilution to working concentration. |
Gene Name : | IL15 interleukin 15 [ Homo sapiens (human) ] |
Official Symbol : | IL15 |
Synonyms : | IL-15 |
Gene ID : | 3600 |
mRNA Refseq : | NM_000585.5 |
Protein Refseq : | NP_000576.1 |
UniProt ID : | P40933 |
MIM : | 600554 |
Products Types
◆ Recombinant Protein | ||
IL15-370I | Active Recombinant Human IL15 Protein (121 aa), His-tagged | +Inquiry |
Il15-7234M | Active Recombinant Mouse Il15 Protein, His-tagged | +Inquiry |
IL15-212P | Active Recombinant Pig IL15 Protein (Thr49-Ser162), N-His tagged, Animal-free, Carrier-free | +Inquiry |
IL15-1006C | Recombinant Chicken IL15 Protein, His-tagged | +Inquiry |
IL15-134H | Active Recombinant Human IL15 Protein | +Inquiry |
◆ Lysates | ||
IL15-5248HCL | Recombinant Human IL15 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionTechniques discern IL15 and IL2 receptor binding kinetics.
Methods explore IL15's role in autoimmune disease mechanisms.
IL15 knockout models provide insights into its diverse functions.
IL15's influence on memory T cell differentiation investigated.
Immunofluorescence microscopy visualizes IL15 subcellular localization.
Approaches validate IL15's involvement in inflammatory responses.
IL15's role in NK cell cytotoxicity analyzed using assays.
ELISA measures IL15 secretion accurately.
qPCR quantifies IL15's impact on regulatory T cells.
Flow cytometry quantifies IL15-driven T-cell proliferation.
Customer Reviews (3)
Write a reviewMapping protein- interactions in DNA transcription for gene regulation.
Suitable for cytotoxicity assays.
Effective in NK cell activation.
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