Active Recombinant Full Length Human CFL2 Protein, GST-tagged

• Cat.No.: CFL2-2466HF
• Product Overview: Full-length human Cofilin2 [1-166(end) amino acids of accession number NP_068733.1] was expressed as N-terminal GST-fusion protein (46 kDa) using

Specification

• Source: E. coli
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.1% CHAPS, 1 mM DTT, 10% glycerol, pH 7.5
• Bio-activity: The phosphorylational ability of the protein was determined by ELISA.The substrate protein was incubated with the indicated enzyme, andafter stopping kinase reaction by EDTA, the reaction solution wastransferred into glutathione-coated plate. Phosphorylation was detected by anti-phospho antibody and HRP-labeled anti-rabbit IgG
• Protein length: 1-166(end)
• Purity: 100%
• Applications: SDS-PAGE
• Storage: Store at -80C. Avoid repeating freeze-thaws.

Gene Information

• Gene Name: cofilin 2 (muscle)
• Official Symbol: CFL2
• Protein Refseq: NP_068733.1
• UniProt ID: Q9Y281

Reviews

05/23/2022

It has been extensively used in protein-protein interaction studies, enzymatic assays, and structural analyses, showcasing its reliability and adaptability in diverse research areas.

11/13/2021

I am certain of obtaining reliable and reproducible results, enabling me to contribute to scientific progress and make new discoveries.

11/07/2017

I highly recommend the CFL2 Protein for its outstanding performance in ELISA assays.

Q&As

Are there any ongoing clinical trials targeting CFL2 for therapeutic purposes?

It's important to check current clinical trial databases for the latest information, but research exploring CFL2 as a therapeutic target is ongoing.

How does CFL2 relate to cardiac diseases?

CFL2 is involved in maintaining the structure and function of cardiac muscle cells, and its dysregulation has been linked to conditions such as cardiomyopathies.

Are there diagnostic applications for CFL2 in muscle-related disorders?

Research suggests that analyzing CFL2 levels and activity could serve as diagnostic markers for certain muscle-related disorders.

How does CFL2 interact with other proteins in the context of muscle function?

CFL2 interacts with actin and other regulatory proteins to modulate the dynamics of the actin cytoskeleton, influencing cellular processes crucial for muscle function.

Can CFL2 be a potential therapeutic target for muscle-related disorders?

Investigating CFL2 as a therapeutic target is an active area of research, with the aim of developing interventions for conditions characterized by impaired muscle function.