Active Recombinant Human ALPPL2 protein, His-Avi-tagged, Biotinylated
Cat.No. : | ALPPL2-2862H |
Product Overview : | Biotinylated Recombinant Human ALPPL2 protein(Ile 20-Asp 503), fused with His and Avi tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris,150 mM NaCl,pH7.5 with trehalose as protectant. |
Bio-activity : | Immobilized Biotinylated Human ALPG / ALPPL2 Protein,His,Avitag at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate can bind Anti-ALPG / ALPPL2 with a linear range of 0.1-4 ng/mL. |
Molecular Mass : | This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™)The protein has a calculated MW of 56.2 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Ile 20-Asp 503 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
Storage : | For long term storage, the product should be stored at lyophilized state at-20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after storage at:-20°C to-70°C for 12 months in lyophilized state;-70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | ALPPL2 alkaline phosphatase, placental-like 2 [ Homo sapiens ] |
Official Symbol : | ALPPL2 |
Synonyms : | ALPPL2; alkaline phosphatase, placental-like 2; alkaline phosphatase, placental-like; ALP-1; Nagao isozyme; germ cell alkaline phosphatase; alkaline phosphatase Nagao isozyme; placental-like alkaline phosphatase; testicular and thymus alkaline phosphatase; ALPG; GCAP; ALPPL; |
Gene ID : | 251 |
mRNA Refseq : | NM_031313 |
Protein Refseq : | NP_112603 |
MIM : | 171810 |
UniProt ID : | P10696 |
Products Types
◆ Recombinant Protein | ||
Alppl2-126M | Recombinant Mouse Alppl2 Protein, His&GST-tagged | +Inquiry |
ALPPL2-1993H | Recombinant Human ALPPL2 Protein, MYC/DDK-tagged | +Inquiry |
ALPPL2-490M | Recombinant Mouse ALPPL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALPPL2-496H | Recombinant Human ALPPL2 Protein, GST-tagged | +Inquiry |
ALPPL2-1576M | Recombinant Mouse ALPPL2 protein, His-tagged | +Inquiry |
◆ Lysates | ||
ALPPL2-65HCL | Recombinant Human ALPPL2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionManipulating ALPPL2 activity and function holds promise for modulating cellular processes and disease outcomes, potentially offering new therapeutic avenues for metabolic disorders, liver diseases, and lipid-related conditions.
Dysregulation or deficiency of ALPPL2 has been associated with metabolic disorders, liver diseases, and dyslipidemia, highlighting its contribution to the pathogenesis of these conditions.
ALPPL2 may serve as a potential diagnostic biomarker for specific diseases, providing insights into disease progression and therapeutic response, and it could be explored as a therapeutic target for developing interventions in certain pathological contexts.
ALPPL2 participates in cellular processes such as lipid metabolism, cell signaling, and membrane dynamics, and it interacts with other proteins and molecules involved in these processes.
ALPPL2 expression and activity are influenced by various physiological and pathological stimuli, including hormonal regulation, nutrient availability, and disease conditions.
ALPPL2 exhibits a specific expression pattern, with higher levels in certain tissues such as the liver, kidney, and intestine, and it is primarily localized to the plasma membrane or specific subcellular compartments.
ALPPL2 regulates downstream signaling pathways and molecular targets involved in lipid metabolism, cell proliferation, and cell survival, influencing cellular processes such as lipid signaling, membrane trafficking, and cell growth.
ALPPL2 is involved in the metabolism and turnover of its substrates, including lipid molecules and membrane components, playing important roles in cellular lipid homeostasis and membrane remodeling.
ALPPL2 expression is controlled by transcriptional regulators, signaling pathways, and epigenetic modifications that respond to specific cellular signals and environmental cues.
ALPPL2 activity can be modulated by specific factors, such as hormones or lipid-binding proteins, and inhibitors that target its catalytic site or affect its membrane association, leading to altered enzymatic activity and cellular functions.
Customer Reviews (3)
Write a reviewVersatile applications in multiple assay formats.
Easy-to-use assay kit with clear protocols.
Fast and efficient protein purification.
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