Active Recombinant Human CLDN3 Full Length Transmembrane protein(Nanodisc)
Cat.No. : | CLDN3-0298H |
Product Overview : | Recombinant Human CLDN3 Full Length Transmembrane protein(O15551), was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | N/A |
Form : | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Bio-activity : | Elisa plates were pre-coated with Flag Tag CLDN3-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CLDN3-Nanodisc is 6.725ng/ml. |
Molecular Mass : | The human full length CLDN3 protein has a MW of 23.3 kDa. |
Storage : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | CLDN3 claudin 3 [ Homo sapiens ] |
Official Symbol : | CLDN3 |
Synonyms : | CLDN3; claudin 3; C7orf1, CPETR2; claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; HRVP1; RVP1; ventral prostate.1 like protein; CPE-R 2; CPE-receptor 2; ventral prostate.1-like protein; ventral prostate.1 protein homolog; C7orf1; CPE-R2; CPETR2; |
Gene ID : | 1365 |
mRNA Refseq : | NM_001306 |
Protein Refseq : | NP_001297 |
MIM : | 602910 |
UniProt ID : | O15551 |
Products Types
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CLDN3-1442H | Recombinant Human CLDN3 Protein, GST-tagged | +Inquiry |
CLDN3-2789H | Recombinant Human CLDN3 Protein, His-tagged, OVA Conjugated | +Inquiry |
CLDN3-27271TH | Recombinant Human CLDN3 | +Inquiry |
◆ Lysates | ||
CLDN3-7463HCL | Recombinant Human CLDN3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionResearchers are exploring the use of CLDN3 as a target for drug delivery systems, aiming to enhance the specificity of drug delivery to tissues expressing high levels of CLDN3.
CLDN3 is involved in the tight junctions of intestinal epithelial cells, influencing the permeability of the intestinal barrier and playing a role in conditions like IBD.
CLDN3 is under investigation in various conditions, including infectious diseases, where its role in tight junctions may have implications for host-pathogen interactions.
Yes, CLDN3 is implicated in the pathogenesis of inflammatory bowel diseases, and its expression levels are being studied as potential markers for disease severity.
Altered expression of CLDN3 in the blood-brain barrier is associated with certain neurodegenerative diseases, making it a subject of interest for researchers studying these conditions.
Customer Reviews (3)
Write a reviewThe manufacturer's deep understanding of the protein and its applications enables them to promptly and effectively address any issues that may arise during my trials.
It minimizes the risk of protein degradation and maximizes the effectiveness of the protein in various applications, such as cell signaling pathways or metabolic studies.
This stability is particularly advantageous for long-term studies or experiments involving extended incubation periods.
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