Active Recombinant Human CSF2
Cat.No. : | CSF2-22H |
Product Overview : | Recombinant Human GM-CSF is a 14 to 36 kDa globular protein consisting of 128 amino acids, containing two intramolecular disulfide bonds and two N-linked glycosylation sites. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. |
Source : | CHO Cells |
Species : | Human |
Form : | 0.22 um filtered solution in 20 mM TRIS*HCl buffer pH 7.2 |
Bio-activity : | ED50<1 ng/ml, The activity was determined by the dose dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line) |
Molecular Mass : | 14-36 kDA, glycosylated |
AA Sequence : | APARSPSPSTQPWEHVNAIQEARRL LNLSRDTAAEMNETVEVISEMFDLQ EPTCLQTRLELYKQGLRGSLTKLKG PLTMMASHYKQHCPPTPETSCATQI ITFESFKENLKDFLLVIPFDCWEPV QE |
Endotoxin : | < 1.0 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, Determined by SDS-PAGE under reducing conditions and visualized by silver stain. |
Gene Name : | CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Homo sapiens (human) ] |
Official Symbol : | CSF2 |
Synonyms : | CSF2; colony stimulating factor 2 (granulocyte-macrophage); GMCSF; MGC131935; MGC138897; colony stimulating factor 2; molgramostin; sargramostim; granulocyte-macrophage colony stimulating factor; GM-CSF; Molgramostin; Sargramostim; Colony-stimulating factor |
Gene ID : | 1437 |
mRNA Refseq : | NM_000758 |
Protein Refseq : | NP_000749 |
MIM : | 138960 |
UniProt ID : | P04141 |
Chromosome Location : | 5q31.1 |
Pathway : | Calcineurin-regulated NFAT-dependent transcription in lymphocytes; Cytokine Signaling in Immune system; Cytokines and Inflammatory Response |
Function : | cytokine activity; granulocyte macrophage colony-stimulating factor receptor binding; growth factor activity |
Products Types
◆ Recombinant Protein | ||
Csf2-49M | Recombinant Active Mouse CSF2 Protein, His-tagged(N-ter) | +Inquiry |
CSF2-4343O | Recombinant Ovine CSF2 Protein | +Inquiry |
CSF2-45P | Active Recombinant Porcine CSF2 Protein | +Inquiry |
Csf2-033C | Active Recombinant Mouse Csf2 Protein (124 aa) | +Inquiry |
CSF2-43C | Active Recombinant Canine CSF2 Protein | +Inquiry |
◆ Lysates | ||
CSF2-740RCL | Recombinant Rat CSF2 cell lysate | +Inquiry |
CSF2-3008HCL | Recombinant Human CSF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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