Active Recombinant Human CSF2 Protein
Cat.No. : | CSF2-135H |
Product Overview : | Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor is produced by our E.coli expression system and the target gene encoding Ala18-Glu144 is expressed. |
- Specification
- Gene Information
- Related Products
Description : | Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic, monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF can also stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma and adenocarcinoma cell lines. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 5% Mannitol, pH 7.2. |
Bio-activity : | Measured by the dose-dependent stimulation of human TF-1 cell proliferation. ED50 is less than 0.1 ng/ml. Specific Activity of 1.0 x 10^7 IU/ mg. |
Protein Length : | Ala18-Glu144 |
AA Sequence : | MAPARSPSPSTQPWEHVNAIQEARR LLNLSRDTAAEMNETVEVISEMFDL QEPTCLQTRLELYKQGL RGSLTKLKGPLTMMAS HYKQHCPPTPETSCATQIITFESFK ENLKDFLLVIPFDCWEPVQE |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Purity : | >95% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
Reconstitution : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Purity: Greater than 95% as determined by reducing SDS-PAGE. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | CSF2 colony stimulating factor 2 [ Homo sapiens (human) ] |
Official Symbol : | CSF2 |
Synonyms : | Granulocyte-Macrophage Colony-Stimulating Factor; GM-CSF; Colony-Stimulating Factor; CSF; Molgramostin; Sargramostim; GMCSF |
Gene ID : | 1437 |
mRNA Refseq : | NM_000758.4 |
Protein Refseq : | NP_000749.2 |
MIM : | 138960 |
UniProt ID : | P04141 |
Products Types
◆ Lysates | ||
CSF2-3008HCL | Recombinant Human CSF2 cell lysate | +Inquiry |
CSF2-740RCL | Recombinant Rat CSF2 cell lysate | +Inquiry |
CSF2-1008MCL | Recombinant Mouse CSF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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